About: OspA lipoprotein     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • withdrawn (en)
http://linked.open...drugbank/halfLife
  • 1.2 hours (mammalian reticulocytes, in vitro). (en)
http://linked.open...ugbank/indication
  • For prophylactic treatment of Lyme Disease (en)
sameAs
Title
  • OspA lipoprotein (en)
adms:identifier
http://linked.open...mechanismOfAction
  • OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks. (en)
http://linked.open.../drugbank/synonym
  • Outer surface protein A precursor (en)
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...nk/Hydrophobicity
http://linked.open...Isoelectric-Point
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