About: Palifermin

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B412E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B412F-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	#Lexicomp [Internet]. Palifermin. 2014 [cited 1 December 2014]. Available from: http://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/7429#f_interactions (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	Elimination half-life: 4.5 hours (range: 3.3-5.7 hours) (en)
http://linked.open...ugbank/indication	For treatment of oral mucositis associated with chemotherapy and radiation therapy. (en)
sameAs	Palifermin Palifermin
Title	Palifermin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/drugbank/DB00039 http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/genbank/M60828 http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/national-drug-code-directory/55513-520-06 http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/uniprotkb/P21781 http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/pharmgkb/PA164744014 http://linked.opendata.cz/resource/drugbank/drug/DB00039/identifier/wikipedia/Palifermin
http://linked.open...mechanismOfAction	Kepivance binds to the human keratinocyte growth factor (KGF) receptor found on buccal cell surfaces. The binding activates a Ras-MapK (Map kinase) signaling pathway which leads to the transcriptional activation of many proteins important for cell growth and survival. (en)
http://linked.open...drugbank/packager	Amgen Inc. Acs dobfar info sa Baxter healthcare corp
http://linked.open.../drugbank/synonym	FGF-7 (en) Fibroblast growth factor- 7 (en) HBGF-7 (en) KGF (en) Keratinocyte growth factor precursor (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/84-16-00
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0521761
foaf:page	http://www.drugs.com/cdi/palifermin.html http://www.rxlist.com/cgi/generic/kepivance.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B4133-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4132-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Palifermin
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	162394-19-6 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Kepivance 6.25 mg vial
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B4130-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B4131-363D-11E5-9242-09173F13E4C5

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