About: Anistreplase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells. Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase). A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins. (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...ugbank/indication
  • For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction (en)
sameAs
Title
  • Anistreplase (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Anistreplase cleaves the Arg/Val bond in plasminogen to form plasmin. This in turn leads to the degradation of blood clots. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Tissue-type plasminogen activator precursor (en)
  • t- PA (en)
  • t-plasminogen activator (en)
  • tPA (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...y/mesh/hasConcept
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...l/drug/hasATCCode
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 81669-57-0 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...nk/Hydrophobicity
http://linked.open...Isoelectric-Point
http://linked.open...ank/Melting-Point
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