About: Antihemophilic Factor

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B402F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4030-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Titheradge MA, Coore HG: Initial rates of pyruvate transport in mitochondria determined by an "inhibitor-stop" technique. Biochem J. 1975 Sep;150(3):553-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/2157 (en)
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...drugbank/halfLife	8.4-19.3 hrs (en)
http://linked.open...ugbank/indication	For the treatment of hemophilia A, von Willebrand disease and Factor XIII deficiency. (en)
sameAs	Antihemophilic Factor Antihemophilic Factor
Title	Antihemophilic Factor (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/drugbank/DB00025 http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/genbank/M14113 http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/national-drug-code-directory/0026-3782-20 http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/uniprotkb/P00451 http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/pharmgkb/PA164750168 http://linked.opendata.cz/resource/drugbank/drug/DB00025/identifier/wikipedia/Antihemophilic_Factor
http://linked.open...mechanismOfAction	Antihemophilic factor (AHF) is a protein found in normal plasma which is necessary for clot formation. The administration of AHF provides an increase in plasma levels of AHF and can temporarily correct the coagulation defect of patients with hemophilia A (classical hemophilia). (en)
http://linked.open...drugbank/packager	Pfizer Inc. Bayer Healthcare CSL Behring LLC GlaxoSmithKline Inc. Galderma laboratories lp 3M Health Care Ivax pharmaceuticals inc sub teva pharmaceuticals usa Amerisource Health Services Corp. Apotheca Inc.
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/1339477 http://linked.opendata.cz/resource/drugbank/patent/2124690
http://linked.open.../drugbank/synonym	AHF (en) Factor VIII (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/20-28-16
http://linked.open...ynthesisReference	James W. Bloom, "Warm ethanol method for preparation of low fibrinogen antihemophilic factor." U.S. Patent US4478825, issued June, 1955. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0209555
foaf:page	http://www.drugs.com/cdi/antihemophilic-factor-human.html http://www.rxlist.com/cgi/generic2/hemofilm.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B4034-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4033-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...drugbank/category	(en)
http://linked.open...rugbank/clearance	* 4.1 mL/h•kg [Previously treated pediatric patients] (en)
http://linked.open...gbank/containedIn	Monoclate-p 1000 unit kit Monoclate-p 1500 unit kit Monoclate-p 250 unit kit Monoclate-p 500ahfu kit Alphanate 1000-1500 unit vial Alphanate 250-500 unit vial Humate-p 1000 unit kit Humate-p 1200 unit kit Humate-p 2000 unit kit Humate-p 2400 unit kit Humate-p 500 unit kit Humate-p 600 unit kit Koate-dvi 1000 unit kit Koate-dvi 250 unit kit Koate-dvi 500 unit kit Refacto 1000 unit vial Refacto 2000 unit vial Refacto 250 unit vial Refacto 500 unit vial Hemofil m 1701-2000 unit vial Hemofil m 220-400 unit vial Hemofil m 401-800 unit vial Hemofil m 801-1700 unit vial Vecuronium 10 mg/10 ml syringe Doxycycline Hyclate 100 mg capsule Doxycycline hyclate 100 mg tablet Doxycycline hyclate 20 mg tablet Doxycycline Monohydrate 50 mg capsule Helixate fs 500 unit vial Doxycycline Monohydrate 100 mg capsule Vibramycin 50 mg capsule Doxycycline hyclate powder Doxycycline Monohydrate 50 mg tablet Advate 1201-1800 unit vial Advate 1801-2400 unit vial Advate 200-400 unit vial Advate 2400-3600 unit vial Advate 401-800 unit vial Advate 801-1200 unit vial Kogenate fs 1000 unit vial Kogenate fs 250 unit vial Doryx dr 75 mg tablet Doryx 75 mg Enteric Coated Tabs
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B4031-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B4032-363D-11E5-9242-09173F13E4C5

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