About: Asparaginase

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Asparaginase Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	L-asparagine amidohydrolase from E. coli (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B3FE9-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Appel IM, van Kessel-Bakvis C, Stigter R, Pieters R: Influence of two different regimens of concomitant treatment with asparaginase and dexamethasone on hemostasis in childhood acute lymphoblastic leukemia. Leukemia. 2007 Jun 7;. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17554375 # http://www.google.com/patents/EP2046369A2 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	8-30 hrs (en)
http://linked.open...ugbank/indication	For treatment of acute lympocytic leukemia and non-Hodgkins lymphoma (en)
sameAs	Asparaginase Asparaginase
Title	Asparaginase (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00023/identifier/drugbank/DB00023 http://linked.opendata.cz/resource/drugbank/drug/DB00023/identifier/genbank/U00096 http://linked.opendata.cz/resource/drugbank/drug/DB00023/identifier/pharmgkb/PA448492 http://linked.opendata.cz/resource/drugbank/drug/DB00023/identifier/uniprotkb/P37595 http://linked.opendata.cz/resource/drugbank/drug/DB00023/identifier/wikipedia/Asparaginase
http://linked.open...mechanismOfAction	Asparaginase converts asparagine to aspartic acid and ammonia. It facilitates production of oxaloacetate which is needed for general cellular metabolism. Some malignant cells lose the ability to produce asparagine and so the loss of exogenous sources of asparagine leads to cell death. (en)
http://linked.open...drugbank/packager	Actavis elizabeth llc Apotex inc Biovail laboratories inc
http://linked.open.../drugbank/synonym	L-asparagine amidohydrolase (en) Putative L-asparaginase precursor (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/10-00-00
http://linked.open...ynthesisReference	Masao Nambu, "Process for producing immobilized L-asparaginase preparations for the therapy of leukemia." U.S. Patent US4617271, issued January, 1977. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0001815
foaf:page	http://www.drugs.com/cdi/asparaginase.html http://www.rxlist.com/cgi/generic3/asparaginase.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B3FED-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B3FEC-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Asparaginase
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	9015-68-3 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Elspar 10000 unit vial
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B3FEA-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B3FEB-363D-11E5-9242-09173F13E4C5

Faceted Search & Find service v1.16.116 as of Feb 22 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of Feb 22 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software