About: Secretin

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	This drug is the synthetic form of natural secretin. It is prepared using solid phase peptide synthesis. Secretin is a peptide hormone produced in the S cells of the duodenum. Its main effect is to regulate the pH of the small intestine’s contents through the control of gastric acid secretion and buffering with bicarbonate. It was the first hormone to be discovered. (en)
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...ugbank/indication	For diagnosis of pancreatic exocrine dysfunction and gastrinoma (en)
http://linked.open...bank/manufacturer	A-S Medication Solutions LLC Atlantic Biologicals Corporation
sameAs	Secretin Secretin
Title	Secretin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00021/identifier/drugbank/DB00021 http://linked.opendata.cz/resource/drugbank/drug/DB00021/identifier/pharmgkb/PA164760844 http://linked.opendata.cz/resource/drugbank/drug/DB00021/identifier/wikipedia/Secretin
http://linked.open...mechanismOfAction	Secretin binds to the secretin receptor found on the lining of S cells in the duodenum and G cells in the stomach. Binding leads to the secrection of bicarbonate or the reduction of the secretion of gastrin. Properly functioning organs (duodenum, pancreas and stomach) should be responsive to this hormone (en)
http://linked.open...drugbank/packager	Apotex Inc.
http://linked.open...ynthesisReference	Martin Bickel, Rolf Geiger, Richard Leeb, Walter Petri, "Secretin preparations with intensified and protracted action, process for their manufacture, their use as well as dihydroxybenzoyl-L-tyrosine." U.S. Patent US4302448, issued August, 1964. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0019589
foaf:page	http://www.drugs.com/human_secretin.html http://www.rxlist.com/cgi/generic3/secretin.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B3FCA-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B3FC9-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Secretin
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Cyclophosphamide 50 mg tablet
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B3FC7-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B3FC8-363D-11E5-9242-09173F13E4C5

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