About: Epoetin alfa

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Human erythropoietin (recombinant), produced by CHO cells. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B3F7D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F7E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F7F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F80-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F81-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F82-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F83-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F84-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F85-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F86-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F87-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For treatment of anemia (from renal transplants or certain HIV treatment) (en)
sameAs	Epoetin alfa Epoetin alfa
Title	Epoetin alfa (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/drugbank/DB00016 http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/genbank/X02158 http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/national-drug-code-directory/55513-126-10 http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/uniprotkb/P01588 http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/pharmgkb/PA10072 http://linked.opendata.cz/resource/drugbank/drug/DB00016/identifier/wikipedia/Epoetin_alfa
http://linked.open...mechanismOfAction	Binding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation. (en)
http://linked.open...drugbank/packager	Amgen Inc. Centocor Ortho Biotech Inc. DSM Corp. Janssen-Ortho Inc. JHP Pharmaceuticals LLC Ortho-McNeil-Janssen Pharmaceuticals Inc. AstraZeneca Inc.
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/1339047
http://linked.open.../drugbank/synonym	Erythropoietin precursor (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/20-16-00
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0028770
foaf:page	http://www.drugs.com/cdi/epoetin-alfa.html http://www.rxlist.com/cgi/generic/epoetin.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B3F8B-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B3F8A-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	113427-24-0 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...rugbank/clearance	* 20.2 +/- 15.9 mL/h/kg [150 Units/kg SC TIW, Week 1 when anemic cancer patients were receiving chemotherapy] * 23.6 +/- 9.5 mL/h/kg [150 Units/kg SC TIW, Week 3 when anemic cancer patients were not receiving chemotherapy] * 9.2 +/- 4.7 mL/h/kg [40,000 Units/kg SC TIW, Week 1 when anemic cancer patients were receiving chemotherapy] * 13.9 +/- 7.6 mL/h/kg [40,000 Units/kg SC TIW, Week 3 when anemic cancer patients were not receiving chemotherapy] (en)
http://linked.open...gbank/containedIn	Epogen 2000 unit/ml vial Procrit 2000 unit/ml vial Epogen 3000 unit/ml vial Procrit 3000 unit/ml vial Epogen 4000 unit/ml vial Foscarnet 24 mg/ml infus bttl Epogen 10000 unit/ml vial Epogen 20000 unit/ml vial Epogen 10000 unit/ml Solution 2ml Vial Dicyclomine hcl powder Dicyclomine Hydrochloride 10 mg/ml Dicyclomine 10 mg/ml vial Bentyl 10 mg/ml ampul Bentylol 2 mg/ml Syrup Dicyclomine HCl 10 mg/5ml Solution Bentylol 10 mg Tablet Bentyl 10 mg/5ml Syrup Epogen 40000 unit/ml Solution 1 Box Contains Ten 1ml Vials
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B3F89-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B3F88-363D-11E5-9242-09173F13E4C5

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