About: Effect of age at exposure in 11 underground miners studies

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time. Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time. (en)
Title	Effect of age at exposure in 11 underground miners studies Effect of age at exposure in 11 underground miners studies (en)
skos:prefLabel	Effect of age at exposure in 11 underground miners studies Effect of age at exposure in 11 underground miners studies (en)
skos:notation	RIV/86652052:_____/14:#0000268!RIV15-MV0-86652052
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	1-3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Tomášek, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní ústav radiační ochrany, v.v.i.
http://linked.open...dnocenehoVysledku	13102
http://linked.open...ai/riv/idVysledku	RIV/86652052:_____/14:#0000268
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lung cancer; radon; uranium miners (en)
http://linked.open.../riv/klicoveSlovo	lung cancer uranium miners radon
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[9EEBD2A4C12F]
http://linked.open...i/riv/nazevZdroje	Radiation Protection Dosimetry
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	160
http://linked.open...iv/tvurceVysledku	Tomášek, Ladislav
http://linked.open...ain/vavai/riv/wos	000339953000031
issn	0144-8420
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1093/rpd/ncu068

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