About: Lung cancer mortality among Czech uranium miners

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The study is based on 9978 Czech uranium miners with 1141 lung cancers observed in updated follow-up 1952-2010. Lung cancer risk in relation to cumulated exposure to radon decay products is linear with substantial modifications by time since exposure, age at exposure, and exposure rate. The crude excess relative risk (ERR) per unit exposure in working level months (WLM) in the cohort is 0.0097 (90%CI: 0.0074-0.0127). The ERR/WLM corresponding to exposure rates below 7 working levels (WL) is substantially higher - 0.0145 (90%CI: 0.0109–0.0193). In the final model, the inverse effect of exposure rate is observed for high exposure rates > 7WL with the ERR/WLM reduced to 31% . The ERR/WLM decreases to 32% and 9% in periods 20-29 and 30+ years since exposure in comparison to period 5-19 years since exposure. Simultaneously, the ERR/WLM decreases with age at exposure – 63% and 49% at ages 30-39 and 40+ years in comparison to age at exposure <30 years. The study is based on 9978 Czech uranium miners with 1141 lung cancers observed in updated follow-up 1952-2010. Lung cancer risk in relation to cumulated exposure to radon decay products is linear with substantial modifications by time since exposure, age at exposure, and exposure rate. The crude excess relative risk (ERR) per unit exposure in working level months (WLM) in the cohort is 0.0097 (90%CI: 0.0074-0.0127). The ERR/WLM corresponding to exposure rates below 7 working levels (WL) is substantially higher - 0.0145 (90%CI: 0.0109–0.0193). In the final model, the inverse effect of exposure rate is observed for high exposure rates > 7WL with the ERR/WLM reduced to 31% . The ERR/WLM decreases to 32% and 9% in periods 20-29 and 30+ years since exposure in comparison to period 5-19 years since exposure. Simultaneously, the ERR/WLM decreases with age at exposure – 63% and 49% at ages 30-39 and 40+ years in comparison to age at exposure <30 years. (en)
Title	Lung cancer mortality among Czech uranium miners - 60 years since exposure Lung cancer mortality among Czech uranium miners - 60 years since exposure (en)
skos:prefLabel	Lung cancer mortality among Czech uranium miners - 60 years since exposure Lung cancer mortality among Czech uranium miners - 60 years since exposure (en)
skos:notation	RIV/86652052:_____/12:#0000060!RIV13-MZ0-86652052
http://linked.open...avai/predkladatel	Státní ústav radiační ochrany, v. v. i.
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NS10596)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Tomášek, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní ústav radiační ochrany, v.v.i.
http://linked.open...dnocenehoVysledku	147599
http://linked.open...ai/riv/idVysledku	RIV/86652052:_____/12:#0000060
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lung cancer; radon; uranium miners (en)
http://linked.open.../riv/klicoveSlovo	lung cancer uranium miners radon
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[12BB20B95448]
http://linked.open...i/riv/nazevZdroje	Journal of Radiological Protection
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Health risks from occupational and environmental radon exposure
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	32
http://linked.open...iv/tvurceVysledku	Tomášek, Ladislav
http://linked.open...ain/vavai/riv/wos	000308348500011
issn	0952-4746
number of pages	14 (xsd:int)
http://bibframe.org/vocab/doi	10.1088/0952-4746/32/3/301
is http://linked.open...avai/riv/vysledek of	Lung cancer mortality among Czech uranium miners - 60 years since exposure

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