About: Lung cancer risk from occupational and environmental radon and role of smoking

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://oem.bmj.com/content/68/Suppl_1/A87.2.abstract?sid=2819f88b-4901-4f59-a180-c6337eb705b7
Description	The study is based on two Czech cohorts of U miners and people exposed to high levels of radon in houses. including 1107 and 240 cases of lung cancer. Individual smoking data were collected for most of subjects (68% and 75%, respectively). The relative risk is evaluated in dependence on cumulated exposure with effect modification by time since exposure and smoking. The excess relative risk per unit exposure from earlier periods of exposure (20 years and more) is about 1/3 in comparison to recent exposures (5-19 years). Smoking specific estimates of excess relative risk per unit exposure were 3-5 times higher among never smokers in both studies. The interaction of radon and smoking is evaluated by geometric mixture models. When smoking specific doses to the lungs and modifying effect of time since exposure are used, the combined effect of radon and smoking is close to the additive model. The study is based on two Czech cohorts of U miners and people exposed to high levels of radon in houses. including 1107 and 240 cases of lung cancer. Individual smoking data were collected for most of subjects (68% and 75%, respectively). The relative risk is evaluated in dependence on cumulated exposure with effect modification by time since exposure and smoking. The excess relative risk per unit exposure from earlier periods of exposure (20 years and more) is about 1/3 in comparison to recent exposures (5-19 years). Smoking specific estimates of excess relative risk per unit exposure were 3-5 times higher among never smokers in both studies. The interaction of radon and smoking is evaluated by geometric mixture models. When smoking specific doses to the lungs and modifying effect of time since exposure are used, the combined effect of radon and smoking is close to the additive model. (en)
Title	Lung cancer risk from occupational and environmental radon and role of smoking Lung cancer risk from occupational and environmental radon and role of smoking (en)
skos:prefLabel	Lung cancer risk from occupational and environmental radon and role of smoking Lung cancer risk from occupational and environmental radon and role of smoking (en)
skos:notation	RIV/86652052:_____/11:#0000025!RIV12-MZ0-86652052
http://linked.open...avai/predkladatel	Státní ústav radiační ochrany, v. v. i.
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NS10596)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Tomášek, Ladislav
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní ústav radiační ochrany, v.v.i.
http://linked.open...dnocenehoVysledku	210098
http://linked.open...ai/riv/idVysledku	RIV/86652052:_____/11:#0000025
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lung cancer; radon; smoking (en)
http://linked.open.../riv/klicoveSlovo	lung cancer smoking - drinking alcohol - students of the University of South Bohemia - preventive programmes radon
http://linked.open...ontrolniKodProRIV	[5E5E03EC7F08]
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Health risks from occupational and environmental radon exposure
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Tomášek, Ladislav
http://bibframe.org/vocab/doi	10.1136/oemed-2011-100382.285

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