About: Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant     Goto   Sponge   NotDistinct   Permalink

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  • The mycotoxin ochratoxin A (OTA) can elicit a wide range of toxic properties including embryotoxicity and teratogenicity. OTA crosses the placenta at early gestation rather than in late gestation, maternal OTA exposure may represent a risk for the developing fetus. The study focuses on the assessment of OTA intake of pregnant women (aged 19-40 years) in the first trimester of pregnancy by means OTA levels in 100 blood serum samples by high-performance liquid chromotography with fluorescence detection (HPLC-FD) method and comparison with dietary OTA exposure in pregnant women. Of all, 96% tested serum samples were positive with values ranging from 0.1 to 0.35 ug/l with a mean value of 0.15 ug/l.
  • The mycotoxin ochratoxin A (OTA) can elicit a wide range of toxic properties including embryotoxicity and teratogenicity. OTA crosses the placenta at early gestation rather than in late gestation, maternal OTA exposure may represent a risk for the developing fetus. The study focuses on the assessment of OTA intake of pregnant women (aged 19-40 years) in the first trimester of pregnancy by means OTA levels in 100 blood serum samples by high-performance liquid chromotography with fluorescence detection (HPLC-FD) method and comparison with dietary OTA exposure in pregnant women. Of all, 96% tested serum samples were positive with values ranging from 0.1 to 0.35 ug/l with a mean value of 0.15 ug/l. (en)
Title
  • Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant
  • Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant (en)
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  • Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant
  • Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant (en)
skos:notation
  • RIV/75010330:_____/13:00010259!RIV14-MZ0-75010330
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  • I, P(NT12051), S
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  • 8
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  • 93170
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  • RIV/75010330:_____/13:00010259
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  • biomarker; dietary exposure; maternal exposure; ochratoxin A; OTA; pregnancy (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [9097CB4FE3DE]
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  • Biomarkers
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  • 18
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  • Dofková, Marcela
  • Dvořák, V.
  • Ostrý, Vladimír
  • Malíř, F.
  • Roubal, T.
  • Dohnal, V.
http://linked.open...ain/vavai/riv/wos
  • 000327504100006
issn
  • 1354-750X
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/1354750X.2013.845609
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