About: The association of taxane resistance genes with the clinical course of ovarian carcinoma

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Expression levels of putative markers of taxane resistance in carcinoma tissues and paired peritoneal samples (n=55) and in 16 samples of ovaries without signs of carcinoma were compared with clinical data and the patients time to progression. Associations of protein expression of the proliferation marker Ki-67 with KIF14, PRC1, ABCB1 and CASP2 were found. In conclusion, ABCB1, CASP2, KIF14, PRC1 and CIT genes seem to associate with surrogate markers of ovarian carcinoma progression and CIT gene associates with therapy outcome. Expression levels of putative markers of taxane resistance in carcinoma tissues and paired peritoneal samples (n=55) and in 16 samples of ovaries without signs of carcinoma were compared with clinical data and the patients time to progression. Associations of protein expression of the proliferation marker Ki-67 with KIF14, PRC1, ABCB1 and CASP2 were found. In conclusion, ABCB1, CASP2, KIF14, PRC1 and CIT genes seem to associate with surrogate markers of ovarian carcinoma progression and CIT gene associates with therapy outcome. (en)
Title	The association of taxane resistance genes with the clinical course of ovarian carcinoma The association of taxane resistance genes with the clinical course of ovarian carcinoma (en)
skos:prefLabel	The association of taxane resistance genes with the clinical course of ovarian carcinoma The association of taxane resistance genes with the clinical course of ovarian carcinoma (en)
skos:notation	RIV/75010330:_____/13:00010095!RIV14-MZ0-75010330
http://linked.open...avai/predkladatel	Státní zdravotní ústav
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(ED2.1.00/03.0076), P(NS9803), S
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Brynychová, Veronika Souček, Pavel Gut, Ivan Václavíková, Radka Ehrlichová, Marie Mohelníková-Duchoňová, Beatrice
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní zdravotní ústav, příspěvková organizace
http://linked.open...dnocenehoVysledku	62357
http://linked.open...ai/riv/idVysledku	RIV/75010330:_____/13:00010095
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ovarian carcinoma; cancer; gene expression; taxanes; chemotherapy (en)
http://linked.open.../riv/klicoveSlovo	gene expression cancer ovarian carcinoma chemotherapy taxanes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[879D0FB622C6]
http://linked.open...i/riv/nazevZdroje	Genomics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Biomedical Centre of the Faculty of Medicine in Pilsen Resistance of breast and ovarian cancer to cytostatics due to ABC transporters and relation of kinesins to prognosis and prediction
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	102
http://linked.open...iv/tvurceVysledku	Souček, Pavel Rob, L. Václavíková, Radka Gut, Ivan Pluta, M. Ehrlichová, Marie Kodet, R. Mrhalová, M. Mohelníková-Duchoňová, Beatrice Hrdý, J. Brynychová, Veronika
http://linked.open...ain/vavai/riv/wos	000322848500004
issn	0888-7543
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ygeno.2013.03.005

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