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Description
| - V Evropě až 35% mladých dospělých jsou nosiči obligátního komensála, Neisseria meningitidis. Nedávné studie prokázaly rozsáhlou různorodost kmenů izolovaných z nosičů oproti omezenému počtu hypervirulentních kmenů spojených s invazivním onemocněním. Novéúdaje ukazují na významné rozdíly v patogenitě mezi meningokokovými klony a v rozšíření multilokusových sekvenčních typů v izolátech z bezpříznakových nosičů. Současné nosičství více jak jednoho kmene v hrtanu je vzácné, ale občas se vyskytne. Komensáln í sdružení určitých klonů s hostitelem je vztahem dlouhodobým. (cs)
- In Europe, as much as 35% of young adults are carriers of Neisseria meningitides, an obligate commensal, at a given time. Recent studies demonstrated the extensive genetic diversity of the strains isolated from carriers, in comparison with a limited number of hypervirulent strains associated with invasive disease. New data indicate significant differences in pathogenicity between meningococcal clones and in the distribution of multilocus sequence types among isolates from asymptomatic carriers. Simultaneous carriage of more than one meningococcal strain in the throat is rare, but occasionally occurs. The commensal association of particular clones with a host is a long-term relationship. Further investigations of the carrier state are warranted.
- In Europe, as much as 35% of young adults are carriers of Neisseria meningitides, an obligate commensal, at a given time. Recent studies demonstrated the extensive genetic diversity of the strains isolated from carriers, in comparison with a limited number of hypervirulent strains associated with invasive disease. New data indicate significant differences in pathogenicity between meningococcal clones and in the distribution of multilocus sequence types among isolates from asymptomatic carriers. Simultaneous carriage of more than one meningococcal strain in the throat is rare, but occasionally occurs. The commensal association of particular clones with a host is a long-term relationship. Further investigations of the carrier state are warranted. (en)
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Title
| - Lessons from meningococcal carriage studies
- Lessons from meningococcal carriage studies (en)
- Ponaučení ze studií nosičství meningokoků (cs)
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skos:prefLabel
| - Lessons from meningococcal carriage studies
- Lessons from meningococcal carriage studies (en)
- Ponaučení ze studií nosičství meningokoků (cs)
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skos:notation
| - RIV/75010330:_____/07:00007329!RIV08-MZ0-75010330
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/75010330:_____/07:00007329
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Neisseria meningitidis; MLST (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - FEMS microbiology reviews
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Křížová, Pavla
- Tzanakaki, Georgina
- Caugant, Dominique A.
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issn
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number of pages
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