About: In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Background: The ability of magnetic particles to be heated up by AC magnetic field has outlined a new effective method for tumour?s treatment ? magnetic hyperthermia. Recently there?ve been attempts to use the energy of electric field for the same purpose. The electro hyperthermia method works due to the significant difference in conductivity of malignant and healthy tissue which makes the method selective. Although the penetration depth of electric field is smaller than in the case of magnetic field, its absorption efficiency is higher. In order to increase the efficiency further we proposed to use electrically lossy magnetic fluid as a mediator in electro-hyperthermia. Methods: To test the effect of mediator on the heating of malignant cells, the hepatocellular carcinoma cell line (Hep G2; ATCC) and human immortalized non-tumorigenic keratinocyte cell line (HaCaT; CLS were used) were used. As the mediator, maghemite-based ferrofluid with special morphology giving rise to high dielectric losses at Background: The ability of magnetic particles to be heated up by AC magnetic field has outlined a new effective method for tumour?s treatment ? magnetic hyperthermia. Recently there?ve been attempts to use the energy of electric field for the same purpose. The electro hyperthermia method works due to the significant difference in conductivity of malignant and healthy tissue which makes the method selective. Although the penetration depth of electric field is smaller than in the case of magnetic field, its absorption efficiency is higher. In order to increase the efficiency further we proposed to use electrically lossy magnetic fluid as a mediator in electro-hyperthermia. Methods: To test the effect of mediator on the heating of malignant cells, the hepatocellular carcinoma cell line (Hep G2; ATCC) and human immortalized non-tumorigenic keratinocyte cell line (HaCaT; CLS were used) were used. As the mediator, maghemite-based ferrofluid with special morphology giving rise to high dielectric losses at (en)
Title	In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia (en)
skos:prefLabel	In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia (en)
skos:notation	RIV/70883521:28610/10:63509215!RIV11-MSM-28610___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM7088352101)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Valášek, Pavel Humpolíček, Petr Vilčáková, Jarmila Moučka, Robert Sáha, Petr Kazantseva, Natalia
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Tomáše Bati ve Zlíně / Univerzitní institut
http://linked.open...dnocenehoVysledku	263295
http://linked.open...ai/riv/idVysledku	RIV/70883521:28610/10:63509215
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hyperthermia; in vitro; cancer (en)
http://linked.open.../riv/klicoveSlovo	cancer hyperthermia in vitro
http://linked.open...ontrolniKodProRIV	[5BF76FD7D915]
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Humpolíček, Petr Sáha, Petr Valášek, Pavel Kazantseva, Natalia Moučka, Robert Vilčáková, Jarmila
http://linked.open...n/vavai/riv/zamer	Multifunctional Composite Systems Based on Natural and Synthetic Polymers
http://localhost/t...ganizacniJednotka	28610

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