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  • Hyperthermia is a cancer treatment method with the exposure to temperatures 40-44 0C. It has been observed that these temperatures induce selective cancer cells killing, while the normal cells remain unaffected.The existing RF-hyperthermia systems are based on the following methods: (i) impedance, inducting and capacitive heating in kHz and MHz regions; (ii) antenna (phase) array in 100 MHz region; (iii) microwave radiation over 200 MHz.Among all hyperthermia modalities local heating of the tumor by Magnetic Mediated Hyperthermia (MMH) seem to be the most promising method. In MMH a special magnetic material - mediator is implanted to the tumor and is heated by the application of alternating magnetic field.Generally, two classes of magnetic materials are suggested from the viewpoint of MMH treatment: magnetic fluids (magnetic fluid hyperthermia), and, polymer (gel) magnetic composites (magnetic embolization hyperthermia).The structural, magnetostatic, magnetodynamic and calorimetric properties of obtained material have been studied. It was shown, that by optimizing the parameters of chemical synthesis the materials with high heating characteristics in the alternating magnetic field, applicable in MMH, can be obtained.
  • Hyperthermia is a cancer treatment method with the exposure to temperatures 40-44 0C. It has been observed that these temperatures induce selective cancer cells killing, while the normal cells remain unaffected.The existing RF-hyperthermia systems are based on the following methods: (i) impedance, inducting and capacitive heating in kHz and MHz regions; (ii) antenna (phase) array in 100 MHz region; (iii) microwave radiation over 200 MHz.Among all hyperthermia modalities local heating of the tumor by Magnetic Mediated Hyperthermia (MMH) seem to be the most promising method. In MMH a special magnetic material - mediator is implanted to the tumor and is heated by the application of alternating magnetic field.Generally, two classes of magnetic materials are suggested from the viewpoint of MMH treatment: magnetic fluids (magnetic fluid hyperthermia), and, polymer (gel) magnetic composites (magnetic embolization hyperthermia).The structural, magnetostatic, magnetodynamic and calorimetric properties of obtained material have been studied. It was shown, that by optimizing the parameters of chemical synthesis the materials with high heating characteristics in the alternating magnetic field, applicable in MMH, can be obtained. (en)
Title
  • Iron oxide nanoparticles as heat mediators in magnetic-mediated hyperthermia
  • Iron oxide nanoparticles as heat mediators in magnetic-mediated hyperthermia (en)
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  • Iron oxide nanoparticles as heat mediators in magnetic-mediated hyperthermia
  • Iron oxide nanoparticles as heat mediators in magnetic-mediated hyperthermia (en)
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  • RIV/70883521:28110/12:43869611!RIV13-MSM-28110___
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  • RIV/70883521:28110/12:43869611
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  • iron oxide nanoparticles, cooprecipitation method, magnetic properties, specific loss power, magnetically mediated hyperthermia (en)
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  • Sáha, Petr
  • Kazantseva, Natalia
  • Moučka, Robert
  • Vilčáková, Jarmila
  • Babayan, Vladimir Artur
  • Stepanova, Ilona
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  • 28110
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