About: Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation

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About: Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	2,3,4-Trisubstituted quinolines, substituted with adamantan-1-yl or (adamantan-1-yl)methyl in the 4-position, were prepared from the corresponding admantan-1-yl 2-aminophenyl ketones or admantan-1-ylmethyl 2-aminophenyl ketones and ketones with an α-CH 2 group. These reactions were carried out under neat conditions or in toluene, and the products were obtained in moderate-to-excellent yields. The scope and limitations of the examined procedures are discussed. All new compounds are fully characterized by IR and NMRspectroscopy and mass spectrometry. The molecular structures of five new quinolines, obtained via single-crystal X-ray diffraction analyses, are discussed. 2,3,4-Trisubstituted quinolines, substituted with adamantan-1-yl or (adamantan-1-yl)methyl in the 4-position, were prepared from the corresponding admantan-1-yl 2-aminophenyl ketones or admantan-1-ylmethyl 2-aminophenyl ketones and ketones with an α-CH 2 group. These reactions were carried out under neat conditions or in toluene, and the products were obtained in moderate-to-excellent yields. The scope and limitations of the examined procedures are discussed. All new compounds are fully characterized by IR and NMRspectroscopy and mass spectrometry. The molecular structures of five new quinolines, obtained via single-crystal X-ray diffraction analyses, are discussed. (en)
Title	Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation (en)
skos:prefLabel	Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation (en)
skos:notation	RIV/70883521:28110/12:43867998!RIV13-MSM-28110___
http://linked.open...avai/predkladatel	Fakulta technologická
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM7088352101)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Rouchal, Michal Vícha, Robert Kozubková, Zuzana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Tomáše Bati ve Zlíně / Fakulta technologická
http://linked.open...dnocenehoVysledku	154807
http://linked.open...ai/riv/idVysledku	RIV/70883521:28110/12:43867998
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Single crystal X-ray diffraction analysis; Quinoline derivative; Novel route; NMR-spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	NMR-spectroscopy Novel route Quinoline derivative Single crystal X-ray diffraction analysis
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[EAD3116E7E20]
http://linked.open...i/riv/nazevZdroje	Helvetica Chimica Acta
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	95
http://linked.open...iv/tvurceVysledku	Nečas, Marek Rouchal, Michal Vícha, Robert Kozubková, Zuzana
http://linked.open...ain/vavai/riv/wos	000305295200016
http://linked.open...n/vavai/riv/zamer	Multifunctional Composite Systems Based on Natural and Synthetic Polymers
issn	0018-019X
number of pages	15 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/hlca.201100432
http://localhost/t...ganizacniJednotka	28110
is http://linked.open...avai/riv/vysledek of	Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation

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