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Description
  • Several new 2,6,9-trisubstituted purines have been synthesised from 2,6-dichloropurine via alkylation at N-9 followed by SN-Ar at C-6. Prepared compounds were fully characterised using structural methods ESI-MS and NMR as well as their inhibitory activity toward CDK2 was assayed.
  • Several new 2,6,9-trisubstituted purines have been synthesised from 2,6-dichloropurine via alkylation at N-9 followed by SN-Ar at C-6. Prepared compounds were fully characterised using structural methods ESI-MS and NMR as well as their inhibitory activity toward CDK2 was assayed. (en)
Title
  • The Synthesis and Biological Activity of Novel Trisubstituted Purines
  • The Synthesis and Biological Activity of Novel Trisubstituted Purines (en)
skos:prefLabel
  • The Synthesis and Biological Activity of Novel Trisubstituted Purines
  • The Synthesis and Biological Activity of Novel Trisubstituted Purines (en)
skos:notation
  • RIV/70883521:28110/09:63508157!RIV10-MSM-28110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GP203/06/P362), Z(MSM7088352101)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 345056
http://linked.open...ai/riv/idVysledku
  • RIV/70883521:28110/09:63508157
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • benzylamines; 1-adamantyl; purines; CDK (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [FB93AA971B2B]
http://linked.open...v/mistoKonaniAkce
  • Wien
http://linked.open...i/riv/mistoVydani
  • Vídeň
http://linked.open...i/riv/nazevZdroje
  • 13. Öesterreichische Chemietage
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Rouchal, Michal
  • Vícha, Robert
  • Čmelík, R.
  • Marek, R.
  • Nečas, M.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Gesellschaft Öesterreichischer Chemiker
https://schema.org/isbn
  • 978-3-900554-66-8
http://localhost/t...ganizacniJednotka
  • 28110
is http://linked.open...avai/riv/vysledek of
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