About: BrachyView, a novel inbody imaging system for HDR prostate brachytherapy: design and Monte Carlo feasibility study     Goto   Sponge   NotDistinct   Permalink

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Description
  • High dose rate (HDR) brachytherapy is a form of radiation therapy for treating prostate cancer whereby a high activity radiation source is moved between predefined positions inside applicators inserted within the treatment volume. Accurate positioning of the source is essential in delivering the desired dose to the target area while avoiding radiation injury to the surrounding tissue. In this paper, HDR BrachyView, a novel inbody dosimetric imaging system for real time monitoring and verification of the radioactive seed position in HDR prostate brachytherapy treatment is introduced. The current prototype consists of a 15 x 60 mm(2) silicon pixel detector with a multipinhole tungsten collimator placed 6.5 mm above the detector. Seven identical pinholes allow full imaging coverage of the entire treatment volume. The combined pinhole and pixel sensor arrangement is geometrically designed to be able to resolve the three-dimensional location of the source. The probe may be rotated to keep the whole prostate within the transverse plane. The purpose of this paper is to demonstrate the efficacy of the design through computer simulation, and to estimate the accuracy in resolving the source position (in detector plane and in 3D space) as part of the feasibility study for the BrachyView project.
  • High dose rate (HDR) brachytherapy is a form of radiation therapy for treating prostate cancer whereby a high activity radiation source is moved between predefined positions inside applicators inserted within the treatment volume. Accurate positioning of the source is essential in delivering the desired dose to the target area while avoiding radiation injury to the surrounding tissue. In this paper, HDR BrachyView, a novel inbody dosimetric imaging system for real time monitoring and verification of the radioactive seed position in HDR prostate brachytherapy treatment is introduced. The current prototype consists of a 15 x 60 mm(2) silicon pixel detector with a multipinhole tungsten collimator placed 6.5 mm above the detector. Seven identical pinholes allow full imaging coverage of the entire treatment volume. The combined pinhole and pixel sensor arrangement is geometrically designed to be able to resolve the three-dimensional location of the source. The probe may be rotated to keep the whole prostate within the transverse plane. The purpose of this paper is to demonstrate the efficacy of the design through computer simulation, and to estimate the accuracy in resolving the source position (in detector plane and in 3D space) as part of the feasibility study for the BrachyView project. (en)
Title
  • BrachyView, a novel inbody imaging system for HDR prostate brachytherapy: design and Monte Carlo feasibility study
  • BrachyView, a novel inbody imaging system for HDR prostate brachytherapy: design and Monte Carlo feasibility study (en)
skos:prefLabel
  • BrachyView, a novel inbody imaging system for HDR prostate brachytherapy: design and Monte Carlo feasibility study
  • BrachyView, a novel inbody imaging system for HDR prostate brachytherapy: design and Monte Carlo feasibility study (en)
skos:notation
  • RIV/68407700:21670/13:00216015!RIV14-TA0-21670___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(TA01010164)
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 63804
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21670/13:00216015
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Brachytherapy; prostate cancer; pixel detectors; Timepix (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [14C05A6B8640]
http://linked.open...i/riv/nazevZdroje
  • Medical Physics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 40
http://linked.open...iv/tvurceVysledku
  • Bucci, J.
  • Han, Z.
  • Jakůbek, Jan
  • Petasecca, M.
  • Pospíšil, Stanislav
  • Zaider, M.
  • Cutajar, D.
  • Rosenfeld, A. B.
  • Franklin, D. R.
  • Guatelli, S.
  • Lerch, M. L.
  • Safavi-Naeini, M.
http://linked.open...ain/vavai/riv/wos
  • 000321272200019
issn
  • 0094-2405
number of pages
http://bibframe.org/vocab/doi
  • 10.1118/1.4808360
http://localhost/t...ganizacniJednotka
  • 21670
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