About: Boron Doped Nanocrystalline Diamond Films for Biosensing Applications

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	With the rise of antibiotic resistance of pathogenic bacteria there is an increased demand for monitoring the functionality of bacteria membranes, the disruption of which can be induced by peptide-lipid interactions. In this work we attempt to construct and disrupt supported lipid membranes (SLB) on boron doped nanocrystalline diamond (B-NCD). Electrochemical Impedance Spectroscopy (EIS) was used to study in situ changes related to lipid membrane formation and disruption by peptide-induced interactions. The observed impedance changes were minimal for oxidized B-NCD samples, but were still detectable in the low frequency part of the spectra. The sensitivity for the detection of membrane formation and disruption was significantly higher for hydrogenated B-NCD surfaces. Data modeling indicates large changes in the electrical charge when an electrical double layer is formed at the B-NCD/SLB interface, governed by ion absorption. By contrast, for oxidized B-NCD surfaces With the rise of antibiotic resistance of pathogenic bacteria there is an increased demand for monitoring the functionality of bacteria membranes, the disruption of which can be induced by peptide-lipid interactions. In this work we attempt to construct and disrupt supported lipid membranes (SLB) on boron doped nanocrystalline diamond (B-NCD). Electrochemical Impedance Spectroscopy (EIS) was used to study in situ changes related to lipid membrane formation and disruption by peptide-induced interactions. The observed impedance changes were minimal for oxidized B-NCD samples, but were still detectable in the low frequency part of the spectra. The sensitivity for the detection of membrane formation and disruption was significantly higher for hydrogenated B-NCD surfaces. Data modeling indicates large changes in the electrical charge when an electrical double layer is formed at the B-NCD/SLB interface, governed by ion absorption. By contrast, for oxidized B-NCD surfaces (en)
Title	Boron Doped Nanocrystalline Diamond Films for Biosensing Applications Boron Doped Nanocrystalline Diamond Films for Biosensing Applications (en)
skos:prefLabel	Boron Doped Nanocrystalline Diamond Films for Biosensing Applications Boron Doped Nanocrystalline Diamond Films for Biosensing Applications (en)
skos:notation	RIV/68407700:21460/11:00183657!RIV12-MSM-21460___
http://linked.open...avai/predkladatel	Fakulta biomedicínského inženýrství
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(LD11078), S, Z(MSM6840770012)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Petrák, Václav Vlčková, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta biomedicínského inženýrství
http://linked.open...dnocenehoVysledku	188640
http://linked.open...ai/riv/idVysledku	RIV/68407700:21460/11:00183657
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	biosensor; nanocrystalline diamond; electrochemical impedance spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	biosensor electrochemical impedance spectroscopy nanocrystalline diamond
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[0D63AD9EB04A]
http://linked.open...i/riv/nazevZdroje	Acta Polytechnica
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Real time nanophotonic imaging in cells using nanodiamond particles
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	2011
http://linked.open...iv/tvurceVysledku	Krucky, J. Petrák, Václav Vlčková, Marie
http://linked.open...n/vavai/riv/zamer	Transdisciplinární výzkum v oblasti biomedicínského inženýrství II
issn	1210-2709
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	21460
is http://linked.open...avai/riv/vysledek of	Boron Doped Nanocrystalline Diamond Films for Biosensing Applications Boron Doped Nanocrystalline Diamond Films for Biosensing Applications

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