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Description
  • Although other methods exist for monitoring gastrointestinal motility and contractility, this study exclusively provides direct and quantitative measurements of the forces experienced by an orally ingested pill. We report motive forces and torques calculated from real-time, in vivo measurements of the movement of a magnetic pill in the stomachs of fasted and fed humans. Three-dimensional net force and two-dimensional net torque vectors as a function of time data during gastric residence are evaluated using instantaneous translational and rotational position data. Additionally, the net force calculations described can be applied to high-resolution pill tracking acquired by any modality.
  • Although other methods exist for monitoring gastrointestinal motility and contractility, this study exclusively provides direct and quantitative measurements of the forces experienced by an orally ingested pill. We report motive forces and torques calculated from real-time, in vivo measurements of the movement of a magnetic pill in the stomachs of fasted and fed humans. Three-dimensional net force and two-dimensional net torque vectors as a function of time data during gastric residence are evaluated using instantaneous translational and rotational position data. Additionally, the net force calculations described can be applied to high-resolution pill tracking acquired by any modality. (en)
Title
  • Understanding Gastric Forces Calculated from High-Resolution Pill Tracking
  • Understanding Gastric Forces Calculated from High-Resolution Pill Tracking (en)
skos:prefLabel
  • Understanding Gastric Forces Calculated from High-Resolution Pill Tracking
  • Understanding Gastric Forces Calculated from High-Resolution Pill Tracking (en)
skos:notation
  • RIV/68407700:21460/10:00169001!RIV11-MSM-21460___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6840770012)
http://linked.open...iv/cisloPeriodika
  • 18
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 294302
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21460/10:00169001
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • drug delivery; gastric retention; pill science (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [0156F36E426C]
http://linked.open...i/riv/nazevZdroje
  • Proceedings of the National academy of sciences of the United Stated of America
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 107
http://linked.open...iv/tvurceVysledku
  • Kučera, Pavel
  • Schlageter, V.
  • Laulicht, B.
  • Mathiowitz, E.
  • Tripathi, A.
http://linked.open...ain/vavai/riv/wos
  • 000277310400030
http://linked.open...n/vavai/riv/zamer
issn
  • 0027-8424
number of pages
http://localhost/t...ganizacniJednotka
  • 21460
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