About: Automated Detection of Interphase and Metaphase Nuclei in the FISH Images

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The fluorescence in-situ hybridization (FISH) belongs to the most common cytogenetic methods and is widely applied in routine clinical genetic diagnostics. We are paying attention to FISH analysis of chromosomal aneuploidies - the deviations from chromosomal number. Such analysis is based on evaluation of up to several hundreds of microscopic images. Computer support for this process includes using methods of image processing and data mining. In this paper, we focus on the image processing part in more detail: first, the properties of FISH images are reviewed, then, the processing flow is outlined. Our aim is to find the interphase and metaphase nuclei and the hybridization signals contained in the image. A simple method using the raw and central moments of detected objects as measures to distinguish between the two types of nuclei is proposed. The fluorescence in-situ hybridization (FISH) belongs to the most common cytogenetic methods and is widely applied in routine clinical genetic diagnostics. We are paying attention to FISH analysis of chromosomal aneuploidies - the deviations from chromosomal number. Such analysis is based on evaluation of up to several hundreds of microscopic images. Computer support for this process includes using methods of image processing and data mining. In this paper, we focus on the image processing part in more detail: first, the properties of FISH images are reviewed, then, the processing flow is outlined. Our aim is to find the interphase and metaphase nuclei and the hybridization signals contained in the image. A simple method using the raw and central moments of detected objects as measures to distinguish between the two types of nuclei is proposed. (en)
Title	Automated Detection of Interphase and Metaphase Nuclei in the FISH Images Automated Detection of Interphase and Metaphase Nuclei in the FISH Images (en)
skos:prefLabel	Automated Detection of Interphase and Metaphase Nuclei in the FISH Images Automated Detection of Interphase and Metaphase Nuclei in the FISH Images (en)
skos:notation	RIV/68407700:21260/12:00198317!RIV13-GA0-21260___
http://linked.open...avai/predkladatel	Fakulta dopravní
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP102/11/1795), P(TA01010931), Z(AV0Z10750506)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kovář, Bohumil
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta dopravní
http://linked.open...dnocenehoVysledku	124176
http://linked.open...ai/riv/idVysledku	RIV/68407700:21260/12:00198317
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	FISH; cytogenetic; image processing (en)
http://linked.open.../riv/klicoveSlovo	FISH image processing cytogenetic
http://linked.open...ontrolniKodProRIV	[812EB69A9CCF]
http://linked.open...v/mistoKonaniAkce	Vilamoura
http://linked.open...i/riv/mistoVydani	Porto
http://linked.open...i/riv/nazevZdroje	BIOINFORMATICS 2012 - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms
http://linked.open...in/vavai/riv/obor	IN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel selective transforms for non-stationary signal processing System for FISH analysis evaluation support
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Kovář, Bohumil Kočárek, E. Schier, J.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2012-02-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Pokročilé matematické metody získávání, zpracování a využití informací a znalostí ve složitých a nedeterministických systémech
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	SciTePress - Science and Technology Publications
https://schema.org/isbn	978-989-8425-90-4
http://localhost/t...ganizacniJednotka	21260
is http://linked.open...avai/riv/vysledek of	Automated Detection of Interphase and Metaphase Nuclei in the FISH Images

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