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Description
| - One common finding in Huntington's disease (HD) is related to phonatory disruptions that can be perceptually characterized by harshness, strained strangled voice quality, and pitch fluctuations. These alterations of voice occur mainly as a consequence of underlying involuntary contractions, variable muscle tone, or even tremor of laryngeal musculature. Recently, several new acoustic analysis methods have been introduced to capture different aspects of these phonatory abnormalities. In this report, we summarize objective acoustic metrics suitable for assessment of phonatory dysfunction and provide their classification accuracy in separation between patients with HD and healthy controls. For this purpose, data consists of 272 phonations collected from 34 individuals with HD and 34 healthy controls. As impairment of phonatory function in HD was found across all investigated measurements, voice analysis may potentially serve as a marker of disease progression.
- One common finding in Huntington's disease (HD) is related to phonatory disruptions that can be perceptually characterized by harshness, strained strangled voice quality, and pitch fluctuations. These alterations of voice occur mainly as a consequence of underlying involuntary contractions, variable muscle tone, or even tremor of laryngeal musculature. Recently, several new acoustic analysis methods have been introduced to capture different aspects of these phonatory abnormalities. In this report, we summarize objective acoustic metrics suitable for assessment of phonatory dysfunction and provide their classification accuracy in separation between patients with HD and healthy controls. For this purpose, data consists of 272 phonations collected from 34 individuals with HD and 34 healthy controls. As impairment of phonatory function in HD was found across all investigated measurements, voice analysis may potentially serve as a marker of disease progression. (en)
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Title
| - Acoustic Findings of Voice Disorders in Huntington's Disease Compared to Parkinson's Disease
- Acoustic Findings of Voice Disorders in Huntington's Disease Compared to Parkinson's Disease (en)
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skos:prefLabel
| - Acoustic Findings of Voice Disorders in Huntington's Disease Compared to Parkinson's Disease
- Acoustic Findings of Voice Disorders in Huntington's Disease Compared to Parkinson's Disease (en)
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skos:notation
| - RIV/68407700:21230/13:00210432!RIV14-MSM-21230___
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21230/13:00210432
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Huntington's disease; hyperkinetic dysarthria; dysphonia; acoustic analysis; classification. (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Klempíř, J.
- Majerová, V.
- Roth, J.
- Rusz, Jan
- Růžička, E.
- Čmejla, Roman
- Tykalová, Tereza
- Baborová, E.
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http://localhost/t...ganizacniJednotka
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