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| Description
| - Chronická nezvladatelná bolest beder a dolních končetin může vzniknout jako důsledek neúspěšné operace zad. Tento stav, nazývaný failed-back surgery syndrom, nelze účinně léčit pomocí farmak. Elektrická stimulace dorzální páteřní míchy (SCS) je aplikována pro mírnění bolesti. Podle lékařské hypotézy se oscilační aktivita, které může mít spojitost s analgetickými účinky, může během stimulace objevit v mozkové kůře. Nová metoda detekce byla navržena pro potvrzení přítomnosti oscilací vyvolaných SCS. Analýza EEG byla provedena pomocí výkonové spektrální hustoty, intervalů spolehlivosti a skupinové statistiky sloužící k ověření. Parametry metody byly experimentálně optimalizovány za účelem maximalizace spolehlivosti. V průběhu SCS byly detekovány a lokalizovány statisticky významné změny na stimulačním kmitočtu a/nebo jeho subharmonických či vyšších harmonických složkách na elektrodách v centrální oblasti skalpu u osmi pacientů. (cs)
- Chronic, intractable pain of lower back and lower extremity might develop as the result of unsuccessful surgery of back. This state called failed-back surgery syndrome cannot be effectively treated by pharmacotherapy. Electric stimulation of the dorsal spinal cord (SCS) is applied to relieve the pain. According to the medical hypothesis, oscillatory activity, which might be related to the analgesic effects, may occur in the cortex during the stimulation. To confirm the presence of the SCS induced oscillations, a new method of detection was designed. The analysis of EEG data was performed using power spectral density, confidence intervals, visualization and group statistic for its verification. Parameters of the method were experimentally optimized to maximize its reliability. During ongoing SCS, statistically significant changes were detected and localized at the stimulation frequency and/or its subharmonic or upper harmonic over central midline electrodes in eight patients.
- Chronic, intractable pain of lower back and lower extremity might develop as the result of unsuccessful surgery of back. This state called failed-back surgery syndrome cannot be effectively treated by pharmacotherapy. Electric stimulation of the dorsal spinal cord (SCS) is applied to relieve the pain. According to the medical hypothesis, oscillatory activity, which might be related to the analgesic effects, may occur in the cortex during the stimulation. To confirm the presence of the SCS induced oscillations, a new method of detection was designed. The analysis of EEG data was performed using power spectral density, confidence intervals, visualization and group statistic for its verification. Parameters of the method were experimentally optimized to maximize its reliability. During ongoing SCS, statistically significant changes were detected and localized at the stimulation frequency and/or its subharmonic or upper harmonic over central midline electrodes in eight patients. (en)
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| Title
| - Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density
- Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density (en)
- Detekce korových oscilací vybuzených SCS pomocí výkonové spektrální hustoty (cs)
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| skos:prefLabel
| - Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density
- Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density (en)
- Detekce korových oscilací vybuzených SCS pomocí výkonové spektrální hustoty (cs)
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| skos:notation
| - RIV/68407700:21230/07:03135444!RIV08-MSM-21230___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21230/07:03135444
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - EEG; failed-back surgery syndrome; induced oscillations; power spectral density; spinal cord stimulation (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Sovka, Pavel
- Stančák, Andrej
- Svoboda, Lukáš
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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