About: Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mechanical properties of a single lamella in three perpendicular directions using instrumented nanoindentation. Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mechanical properties of a single lamella in three perpendicular directions using instrumented nanoindentation. (en)
Title	Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella (en)
skos:prefLabel	Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella (en)
skos:notation	RIV/68407700:21220/14:00217611!RIV15-TA0-21220___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP105/10/2305), P(TA01010185)
http://linked.open...iv/cisloPeriodika	cervenec
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Mareš, Tomáš Lukeš, Jaroslav Šepitka, Josef Korsa, Radim
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta strojní
http://linked.open...dnocenehoVysledku	27627
http://linked.open...ai/riv/idVysledku	RIV/68407700:21220/14:00217611
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Osteon; Lamella; Micromechanics; Elastic constants; Nanoindentation (en)
http://linked.open.../riv/klicoveSlovo	Elastic constants Nanoindentation Micromechanics Lamella Osteon
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[DEC9E3621654]
http://linked.open...i/riv/nazevZdroje	Computer Methods in Biomechanics and Biomedical Engineering
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	New materials and coatings for joint replacement bionical design Morphometry and mechanical properties of trabecular bone assessed by methods of micromechanics and numerical modelling
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	17
http://linked.open...iv/tvurceVysledku	Lukeš, Jaroslav Mareš, Tomáš Šepitka, Josef Korsa, Radim Kytyr, D.
issn	1025-5842
number of pages	2 (xsd:int)
http://bibframe.org/vocab/doi	10.1080/10255842.2014.931078
http://localhost/t...ganizacniJednotka	21220

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