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| rdf:type
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| Description
| - Biomechanical loading affects bone structures. The anabolic effects of cyclic biomechanical loading on bone tissue are influenced by the frequency of loading. Mechanotransduction appears to involve a complex interaction between extracellular fluid shear forces and cellular mechanics. Bone cells are activated by both the cyclic fluid shear stresses and transported ions/molecules in fluid flow. The cyclic loading stimulates new bone formation through (for example) integrin linkages and ion channels. Cyclic stress/strain changes in bone and the cyclic fluid flow in intercellular networks can be induced by the dynamic electronic fixative (EDF). The dynamic effects of EDF stimulate the distraction osteogenesis (desmogenesis). Increasing the rate or frequency by which dynamic loading is applied greatly improves bone tissue mechanosensitivity, possibly due to loading-induced extracellular fluid forces around bone cells, that serve as mechanosensors. The elongation of long bones by EDF is accompanied by the gradual stretching and/or oscillations of the callus between bone fragments. Defined microoscilations of callus between bone fragments initiated by predetermined external force effects very efficiently regulate the healing velocity, the corticalisation – the rise of load bearing tissue structures and the development of elastic and viscoelastic properties of new bone tissue. The active load cycles can be interrupted by the defined tranquillity also. The EDF regulates both strain frequencies and amplitude modulations also. EDF presents the effective clinical tool for software regulated osteogenic stimulations within the callus.
- Biomechanical loading affects bone structures. The anabolic effects of cyclic biomechanical loading on bone tissue are influenced by the frequency of loading. Mechanotransduction appears to involve a complex interaction between extracellular fluid shear forces and cellular mechanics. Bone cells are activated by both the cyclic fluid shear stresses and transported ions/molecules in fluid flow. The cyclic loading stimulates new bone formation through (for example) integrin linkages and ion channels. Cyclic stress/strain changes in bone and the cyclic fluid flow in intercellular networks can be induced by the dynamic electronic fixative (EDF). The dynamic effects of EDF stimulate the distraction osteogenesis (desmogenesis). Increasing the rate or frequency by which dynamic loading is applied greatly improves bone tissue mechanosensitivity, possibly due to loading-induced extracellular fluid forces around bone cells, that serve as mechanosensors. The elongation of long bones by EDF is accompanied by the gradual stretching and/or oscillations of the callus between bone fragments. Defined microoscilations of callus between bone fragments initiated by predetermined external force effects very efficiently regulate the healing velocity, the corticalisation – the rise of load bearing tissue structures and the development of elastic and viscoelastic properties of new bone tissue. The active load cycles can be interrupted by the defined tranquillity also. The EDF regulates both strain frequencies and amplitude modulations also. EDF presents the effective clinical tool for software regulated osteogenic stimulations within the callus. (en)
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| Title
| - Electronic distraction fixation apparatus stimulates new bone formation in callus
- Electronic distraction fixation apparatus stimulates new bone formation in callus (en)
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| skos:prefLabel
| - Electronic distraction fixation apparatus stimulates new bone formation in callus
- Electronic distraction fixation apparatus stimulates new bone formation in callus (en)
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| skos:notation
| - RIV/68407700:21220/14:00216533!RIV15-MSM-21220___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21220/14:00216533
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - distraction of diaphyses; distraction apparatus; electronic regulation of oscilations; callus; bone stimulation (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Pohybové ústrojí. Pokroky ve výzkumu, diagnostice a terapii
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Lísal, Jaroslav
- Petrtýl, Miroslav
- Vítek, Tomáš
- Denk, František
- Mařík, I.
- Myslivec, R.
- Lerach, Aleš
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
| |
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