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  • Cílem tohoto článku je prezentovat výsledky simulací modelu spojujícího proudění krve s její biochemií. K popisu proudění krve byl použit zobecněný Newtonovský model s proměnnou viskozitou. Pro popis biochemie krve byl použit model založený na soustavě rovnic pro advekci, difuzi a chemické reakce procesu koagulace krve. Trojrozměrné numerické simulace byly provedeny pro kompletní model na případu rovné cévy kruhového průřezu. Numerický kód pro výpočty byl založen na prostorové diskretizaci metodou konečných objemů na strukturované síti a následné integraci v čase užitím vícestupňové metody typu Runge-Kutta. Vytvoření krevní sraženiny a její růst jsou sledovány v blízkosti lokálně poškozené cévní stěny. (cs)
  • The aim of this paper is to present results from a computational study of a coupled fluid-biochemistry model. A generalized Newtonian model with shear-thinning viscosity has been adopted to describe the flow of blood. To simulate the biochemical changes and transport in the coagulation process, a set of coupled advection-diffusion-reaction equations is used. Three-dimensional numerical simulations are carried out for the whole model in a straight vessel with circular cross-section, using a finite volume semi-discretization in space, on structured grids, and a multistage scheme for time integration. Clot formation and growth are investigated in the vicinity of an injured region of the vessel wall.
  • The aim of this paper is to present results from a computational study of a coupled fluid-biochemistry model. A generalized Newtonian model with shear-thinning viscosity has been adopted to describe the flow of blood. To simulate the biochemical changes and transport in the coagulation process, a set of coupled advection-diffusion-reaction equations is used. Three-dimensional numerical simulations are carried out for the whole model in a straight vessel with circular cross-section, using a finite volume semi-discretization in space, on structured grids, and a multistage scheme for time integration. Clot formation and growth are investigated in the vicinity of an injured region of the vessel wall. (en)
Title
  • Numerical Simulation of the Coagulation Dynamics of Blood
  • Numerical Simulation of the Coagulation Dynamics of Blood (en)
  • Numerická simulace dynamiky koagulace krve (cs)
skos:prefLabel
  • Numerical Simulation of the Coagulation Dynamics of Blood
  • Numerical Simulation of the Coagulation Dynamics of Blood (en)
  • Numerická simulace dynamiky koagulace krve (cs)
skos:notation
  • RIV/68407700:21220/08:02144035!RIV09-MSM-21220___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6840770010)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 383525
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21220/08:02144035
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Runge-Kutta; blood coagulation; clot; fibrin; finite-volume; non-Newtonian (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [CE4B5BA89D70]
http://linked.open...i/riv/nazevZdroje
  • Computational and Mathematical Methods in Medicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Bodnár, Tomáš
  • Sequeira, A.
http://linked.open...ain/vavai/riv/wos
  • 000258559000001
http://linked.open...n/vavai/riv/zamer
issn
  • 1748-670X
number of pages
http://localhost/t...ganizacniJednotka
  • 21220
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