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  • New liquid crystalline (LC) materials were prepared by derivatization of lactic acid. Mesomorphic properties were studied and the presence of the SmA*–SmC* or exhibit the twist grain boundary (TGB) phases. The potential of high-performance liquid chromatography (HPLC) to separate enantiomers or diastereoisomers was evaluated. Two different brands of commercial chiral sorbents, both based on modified silica with derivatized polysaccharide. The optimized chiral HPLC method provided a baseline separation of the individual enantiomers for the LC material containing one chiral center. In the case of the more complex compound with two asymmetric carbon atoms, partial separation was reached.
  • New liquid crystalline (LC) materials were prepared by derivatization of lactic acid. Mesomorphic properties were studied and the presence of the SmA*–SmC* or exhibit the twist grain boundary (TGB) phases. The potential of high-performance liquid chromatography (HPLC) to separate enantiomers or diastereoisomers was evaluated. Two different brands of commercial chiral sorbents, both based on modified silica with derivatized polysaccharide. The optimized chiral HPLC method provided a baseline separation of the individual enantiomers for the LC material containing one chiral center. In the case of the more complex compound with two asymmetric carbon atoms, partial separation was reached. (en)
Title
  • Chiral HPLC for a study of the optical purity of new liquid crystalline materials derived from lactic acid
  • Chiral HPLC for a study of the optical purity of new liquid crystalline materials derived from lactic acid (en)
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  • Chiral HPLC for a study of the optical purity of new liquid crystalline materials derived from lactic acid
  • Chiral HPLC for a study of the optical purity of new liquid crystalline materials derived from lactic acid (en)
skos:notation
  • RIV/68378271:_____/14:00435779!RIV15-GA0-68378271
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  • I, P(GA13-14133S), S
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  • 8
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  • 7151
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  • RIV/68378271:_____/14:00435779
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  • lactic acid derivative; smectic phase; high performance liquid chromatography; chiral separation (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [A5F6165E0843]
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  • Phase Transitions
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  • 87
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  • Hamplová, Věra
  • Kašpar, Miroslav
  • Novotná, Vladimíra
  • Sýkora, D.
  • Vojtylová, Terézia
http://linked.open...ain/vavai/riv/wos
  • 000340393600004
issn
  • 0141-1594
number of pages
http://bibframe.org/vocab/doi
  • 10.1080/01411594.2014.893344
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