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  • We employ nanocrystalline diamond (NCD) thin films with average grain sizes of 250 and 80 nm to resolve influence of grain boundaries and sp2 phase on protein adsorption and electronic function of solutiongated field-effect transistors (SGFET). Microscopic (20 u m 60 um) SGFETs are fabricated without gate oxides based on hydrogen-terminated NCD films on glass substrates. We show that NCD with grain sizes down to 80 nm and film thickness of 100 nm is fully operational as SGFET. We find that inherent hysteresis of SGFET transfer characteristics, their reaction time, their negative shift after protein adsorption and cell culturing process, low gate leakage currents and no influence of UV sterilization or rinsing are all independent of the NCD grain size. Thus we propose a microscopic model where the function of NCD SGFET is determined by the H-terminated surface of diamond nanocrystals and its interaction with proteins, not by grain boundaries or sp2 phase in general.
  • We employ nanocrystalline diamond (NCD) thin films with average grain sizes of 250 and 80 nm to resolve influence of grain boundaries and sp2 phase on protein adsorption and electronic function of solutiongated field-effect transistors (SGFET). Microscopic (20 u m 60 um) SGFETs are fabricated without gate oxides based on hydrogen-terminated NCD films on glass substrates. We show that NCD with grain sizes down to 80 nm and film thickness of 100 nm is fully operational as SGFET. We find that inherent hysteresis of SGFET transfer characteristics, their reaction time, their negative shift after protein adsorption and cell culturing process, low gate leakage currents and no influence of UV sterilization or rinsing are all independent of the NCD grain size. Thus we propose a microscopic model where the function of NCD SGFET is determined by the H-terminated surface of diamond nanocrystals and its interaction with proteins, not by grain boundaries or sp2 phase in general. (en)
Title
  • Function of thin film nanocrystalline diamond-protein SGFET independent of grain size
  • Function of thin film nanocrystalline diamond-protein SGFET independent of grain size (en)
skos:prefLabel
  • Function of thin film nanocrystalline diamond-protein SGFET independent of grain size
  • Function of thin film nanocrystalline diamond-protein SGFET independent of grain size (en)
skos:notation
  • RIV/68378271:_____/12:00386606!RIV13-GA0-68378271
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • P(GAP108/12/0996), P(GBP108/12/G108), P(GD202/09/H041), P(KAN400100701), Z(AV0Z10100521)
http://linked.open...iv/cisloPeriodika
  • May
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 137365
http://linked.open...ai/riv/idVysledku
  • RIV/68378271:_____/12:00386606
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nanocrystalline diamond; solution-gated field-effect transistors (SGFETs); fetal bovine serum; osteoblastic cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [3256312E2E53]
http://linked.open...i/riv/nazevZdroje
  • Sensors and Actuators B - Chemical
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 166-167
http://linked.open...iv/tvurceVysledku
  • Brož, A.
  • Kalbáčová, M.
  • Kromka, Alexander
  • Krátká, Marie
  • Rezek, Bohuslav
  • Ukraintsev, Egor
  • Ledinský, Martin
http://linked.open...ain/vavai/riv/wos
  • 000305356900035
http://linked.open...n/vavai/riv/zamer
issn
  • 0925-4005
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.snb.2012.02.049
is http://linked.open...avai/riv/vysledek of
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