About: Role of a capacitation-related protein on some sperm functional parameters.

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About: Role of a capacitation-related protein on some sperm functional parameters. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In previous studies a series of Mabs against boar capacitated sperm have been produced. One of these Mabs - 4B12 - was found to recognize a surface membrane-associated protein located in the acrosome portion of the spermatozoa that became accessible to antibody after capacitation. In biological experiments it was shown that Mab 4B12 significantly inhibited boar sperm-porcine ZP binding. In attempts to investigate the mechanisms by which Mab 4B12 affected sperm-ZP binding, the role of the cognate protein on some functional parameters such as sperm motility and ability of the capacitated spermatozoa to undergo AR was studied. Experimental models of premature AR and AR physiologically induced with ZP were applied to study the effect of Mab 4B12 on boar sperm AR using PSA staining to estimate the acrosome-reacted state of spermatozoa. Sperm motility characteristics were determined by the time-exposure photokinesigraphic method. The results obtained in the present study, together with previously establishe In previous studies a series of Mabs against boar capacitated sperm have been produced. One of these Mabs - 4B12 - was found to recognize a surface membrane-associated protein located in the acrosome portion of the spermatozoa that became accessible to antibody after capacitation. In biological experiments it was shown that Mab 4B12 significantly inhibited boar sperm-porcine ZP binding. In attempts to investigate the mechanisms by which Mab 4B12 affected sperm-ZP binding, the role of the cognate protein on some functional parameters such as sperm motility and ability of the capacitated spermatozoa to undergo AR was studied. Experimental models of premature AR and AR physiologically induced with ZP were applied to study the effect of Mab 4B12 on boar sperm AR using PSA staining to estimate the acrosome-reacted state of spermatozoa. Sperm motility characteristics were determined by the time-exposure photokinesigraphic method. The results obtained in the present study, together with previously establishe (en)
Title	Role of a capacitation-related protein on some sperm functional parameters. Role of a capacitation-related protein on some sperm functional parameters. (en)
skos:prefLabel	Role of a capacitation-related protein on some sperm functional parameters. Role of a capacitation-related protein on some sperm functional parameters. (en)
skos:notation	RIV/68378050:_____/02:23033150!RIV/2004/GA0/A23004/N
http://linked.open.../vavai/riv/strany	232;236
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/02/1373), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	48
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Pěknicová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	662604
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/02:23033150
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	zona pellucida; acrosome reaction; boar spermatozoa (en)
http://linked.open.../riv/klicoveSlovo	acrosome reaction boar spermatozoa zona pellucida
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[B768C174DF82]
http://linked.open...i/riv/nazevZdroje	Folia biologica
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Sperm proteins and ubiquitination of acromose in human sperm with normal and pathological spermiogram
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	2002
http://linked.open...iv/tvurceVysledku	Pěknicová, Jana Ivanova, M. Mollova, M. Kyurkchiev, S. Djarkova, T. Nedkova, R.
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0015-5500
number of pages	5 (xsd:int)

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