About: bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.

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About: bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The development of red blood cells from progenitors requires the interplay of specific extracellular factors and intracellular regulators. We show that cooperation of basic fibroblast growth factor (bFGF) with transcriptional regulators - mybproteins, represents an important factor for determining erythroid lineage choice and sustained proliferation of early erythroid cells. These findings unravel a so far unidentified link between extracellular signaling and Myb in hematopoietic cells. The development of red blood cells from progenitors requires the interplay of specific extracellular factors and intracellular regulators. We show that cooperation of basic fibroblast growth factor (bFGF) with transcriptional regulators - mybproteins, represents an important factor for determining erythroid lineage choice and sustained proliferation of early erythroid cells. These findings unravel a so far unidentified link between extracellular signaling and Myb in hematopoietic cells. (en)
Title	bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors. bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors. (en)
skos:prefLabel	bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors. bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors. (en)
skos:notation	RIV/68378050:_____/02:23010491!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany	400;410
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/00/0554), P(GV301/98/K042), P(IAA5052805), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Dvořák, Michal Karafiát, Vít Bartůněk, Petr Pajer, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	639541
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/02:23010491
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Myb; - FGF; - erythropoeisis (en)
http://linked.open.../riv/klicoveSlovo	Myb - FGF - erythropoeisis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[25639D2410BF]
http://linked.open...i/riv/nazevZdroje	Oncogene
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Identification of proteins forming functional complexes with v-Myb oncoprotein Role of v-Myb oncoprotein in the cell cycle regulation of leukaemic monoblasts Acute monoblastic leukaemia: Analysis of molecular mechanisms and possibilities of targeted regulation
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Bartůněk, Petr Dvořák, Michal Karafiát, Vít Pajer, Petr Zenke, M. Blendinger, G.
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0950-9232
number of pages	11 (xsd:int)

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