About: The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.     Goto   Sponge   NotDistinct   Permalink

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  • Inflammation-dependent leukocyte recruitment retained in FucT-VII deficiency is extinguished in FucT-IV(-/-)/FucT-VII (-/-) mice. Double deficiency yields an extreme leukocytosis and contributes to HEV-born L-selectin ligands,since lymphocyte homing retained in FucT-VII(-/) mice is revoked in FucT-IV(-/)/FucT-VII(-/-) mice. These observations reveal essential FucT-IV-dependent contributions to E-, P-, and L-selectin ligand synthesis and to the control of leukocyte recruitment and lymphocyte homing.
  • Inflammation-dependent leukocyte recruitment retained in FucT-VII deficiency is extinguished in FucT-IV(-/-)/FucT-VII (-/-) mice. Double deficiency yields an extreme leukocytosis and contributes to HEV-born L-selectin ligands,since lymphocyte homing retained in FucT-VII(-/) mice is revoked in FucT-IV(-/)/FucT-VII(-/-) mice. These observations reveal essential FucT-IV-dependent contributions to E-, P-, and L-selectin ligand synthesis and to the control of leukocyte recruitment and lymphocyte homing. (en)
Title
  • The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.
  • The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. (en)
skos:prefLabel
  • The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.
  • The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. (en)
skos:notation
  • RIV/68378050:_____/01:23010308!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany
  • 115;126
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 672885
http://linked.open...ai/riv/idVysledku
  • RIV/68378050:_____/01:23010308
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • fucosyltransferase; - selectin ligand; - gene knock-out (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [268490E09A68]
http://linked.open...i/riv/nazevZdroje
  • Immunity
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 15
http://linked.open...iv/tvurceVysledku
  • Malý, Petr
  • Cheng, G.
  • Thall, A. D.
  • Gersten, K. M.
  • Kelly, R. J.
  • Petryniak, B.
  • Rogers, C. E.
  • Smith, P. L.
  • Askari, S. W.
  • Homeister, J. W.
http://linked.open...n/vavai/riv/zamer
issn
  • 1074-7613
number of pages
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