About: Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2642779/summary.html?type=number_search
Description	The invention concerns superparamagnetic nanoparticle probes based on iron oxides with modified surface, method of their preparation and application. The probe is modified on its surface by a modification agent selected from the group consisting of mono-, di- and polysaccharides, poly(amino acid)s and polymers of (meth)acrylic acid derivatives, and form a colloid consisting of particles with narrow size distribution with polydispersity index lower than 1.3, the average size of which ranges from 10 to 30 nm, iron oxide content amounts to 70-99.9 wt.%, the modification agent content makes 0.1-30 wt.%. The probes can be used for labelling cells used in magnetic resonance imaging for monitoring their movement, localization, survival and differentiation especially in detection of pathologies with cell dysfunction and of tissue regeneration and also for labelling and monitoring cells administered for cell therapy purposes in the recipient organism by magnetic resonance. The invention concerns superparamagnetic nanoparticle probes based on iron oxides with modified surface, method of their preparation and application. The probe is modified on its surface by a modification agent selected from the group consisting of mono-, di- and polysaccharides, poly(amino acid)s and polymers of (meth)acrylic acid derivatives, and form a colloid consisting of particles with narrow size distribution with polydispersity index lower than 1.3, the average size of which ranges from 10 to 30 nm, iron oxide content amounts to 70-99.9 wt.%, the modification agent content makes 0.1-30 wt.%. The probes can be used for labelling cells used in magnetic resonance imaging for monitoring their movement, localization, survival and differentiation especially in detection of pathologies with cell dysfunction and of tissue regeneration and also for labelling and monitoring cells administered for cell therapy purposes in the recipient organism by magnetic resonance. (en)
Title	Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application (en)
skos:prefLabel	Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application (en)
skos:notation	RIV/68378041:_____/13:00395817!RIV14-MSM-68378041
http://linked.open...avai/predkladatel	Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(GA203/09/1242), Z(AV0Z40500505), Z(AV0Z50390512)
http://linked.open...cisloPatentuVzoru	CA2642779
http://linked.open...eleniPatentuVzoru	2013-05-14 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Syková, Eva Hájek, Milan Jendelová, Pavla
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	109011
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/13:00395817
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	superparamagnetic; nanoparticles; cell labeling (en)
http://linked.open.../riv/klicoveSlovo	cell labeling superparamagnetic nanoparticles
http://linked.open...ontrolniKodProRIV	[D3BCB818064A]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Gatineau, Québec
http://linked.open...atelePatentuVzoru	Canadian Intellectual Property Office (CIPO)
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Surface-modified magnetic nanoparticles for cell labeling and in vivo and in vitro diagnostics Center for Cell Therapy and Tissue Repair
http://linked.open...UplatneniVysledku	2013
http://linked.open...ydaniPatentuVzoru	CA - Kanada
http://linked.open...iv/tvurceVysledku	Horák, Daniel Syková, Eva Hájek, Milan Jendelová, Pavla Babič, Michal
http://linked.open...mniOchranaPatentu	D - Národní patentový úřad mimo ČR
http://linked.open...avai/riv/vlastnik	Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
http://linked.open...stnikPatentuVzoru	Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i

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