About: Regenerative medicine for the treatment of spinal cord injury: more than just promises?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Spinal cord injury triggers a complex set of events that lead to tissue healing without the restoration of normal function due to the poor regenerative capacity of the spinal cord. Among the range of strategies under investigation, cell-based therapies offer the most promising results, due to the multifactorial roles that these cells can fulfill. In this context, the role of biomaterials is gaining importance. Some of the candidate molecules for the future are discussed in view of the knowledge derived from studying the mechanisms that facilitate the intrinsic regenerative capacity of central nervous system neurons. The future challenge for the multidisciplinary teams working in the field is to translate the knowledge acquired in basic research into effective combinatorial therapies to be applied in the clinic. Spinal cord injury triggers a complex set of events that lead to tissue healing without the restoration of normal function due to the poor regenerative capacity of the spinal cord. Among the range of strategies under investigation, cell-based therapies offer the most promising results, due to the multifactorial roles that these cells can fulfill. In this context, the role of biomaterials is gaining importance. Some of the candidate molecules for the future are discussed in view of the knowledge derived from studying the mechanisms that facilitate the intrinsic regenerative capacity of central nervous system neurons. The future challenge for the multidisciplinary teams working in the field is to translate the knowledge acquired in basic research into effective combinatorial therapies to be applied in the clinic. (en)
Title	Regenerative medicine for the treatment of spinal cord injury: more than just promises? Regenerative medicine for the treatment of spinal cord injury: more than just promises? (en)
skos:prefLabel	Regenerative medicine for the treatment of spinal cord injury: more than just promises? Regenerative medicine for the treatment of spinal cord injury: more than just promises? (en)
skos:notation	RIV/68378041:_____/12:00383908!RIV13-AV0-68378041
http://linked.open...avai/predkladatel	Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GAP304/11/0653), P(GAP304/11/0731), P(IAA500390902), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Syková, Eva Kubinová, Šárka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	164596
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/12:00383908
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Spinal cord injury; cell therapies; stem cells (en)
http://linked.open.../riv/klicoveSlovo	stem cells Spinal cord injury cell therapies
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[115A732CC27E]
http://linked.open...i/riv/nazevZdroje	Journal of Cellular and Molecular Medicine
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of stem cells and biomaterials for spinal cord injury repair Targeted differentiation and transdifferentiation of limbal and mesenchymal stem cells and their therapeutic applications in preclinical models Spinal cord injury repair using biomodified hydrogels with oriented channels
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	16
http://linked.open...iv/tvurceVysledku	Syková, Eva Kubinová, Šárka Mar, F. M. Pêgo, A. P. Sousa, M. M. Vanický, I. Čížková, D.
http://linked.open...ain/vavai/riv/wos	000310555200002
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	1582-1838
number of pages	18 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1582-4934.2012.01603.x
is http://linked.open...avai/riv/vysledek of	Regenerative medicine for the treatment of spinal cord injury: more than just promises?

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