About: Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Hearing thresholds, the strength of the acoustic startle responses and the efficiency of the prepulse inhibition were assessed in young, middle-aged, and aged Long Evans and Fischer 344 rats. Fischer 344 rats showed larger age-related hearing threshold shifts and lower amplitudes of startle responses at an earlier age than in Long Evans rats. A reduction of the prepulse inhibition was observed in aged rats of both strains. The results indicate that the acoustic startle response may serve as an indicator of central presbycusis. Hearing thresholds, the strength of the acoustic startle responses and the efficiency of the prepulse inhibition were assessed in young, middle-aged, and aged Long Evans and Fischer 344 rats. Fischer 344 rats showed larger age-related hearing threshold shifts and lower amplitudes of startle responses at an earlier age than in Long Evans rats. A reduction of the prepulse inhibition was observed in aged rats of both strains. The results indicate that the acoustic startle response may serve as an indicator of central presbycusis. (en)
Title	Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats (en)
skos:prefLabel	Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats (en)
skos:notation	RIV/68378041:_____/12:00383080!RIV13-AV0-68378041
http://linked.open...avai/predkladatel	Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GAP304/12/1342), P(GBP304/12/G069), P(GCP303/11/J005), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Popelář, Jiří Bureš, Zbyněk Syka, Josef Rybalko, Natalia Burianová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	121331
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/12:00383080
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	aging; acoustic startle response; prepulse inhibition (en)
http://linked.open.../riv/klicoveSlovo	acoustic startle response aging prepulse inhibition
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[273F92868C40]
http://linked.open...i/riv/nazevZdroje	Experimental Gerontology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Pathological changes in the central auditory system accompanying aging Project of excellence in the field of neuroscience Neural remodeling after early sound exposures
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	47
http://linked.open...iv/tvurceVysledku	Bureš, Zbyněk Popelář, Jiří Rybalko, Natalia Syka, Josef Burianová, Jana Poon, P. W. F.
http://linked.open...ain/vavai/riv/wos	000312120100011
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0531-5565
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.exger.2012.09.001
is http://linked.open...avai/riv/vysledek of	Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats

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