About: Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.     Goto   Sponge   NotDistinct   Permalink

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  • The manuscript compares chromatographic and immunoassay methods used for the detection of urinary 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG). Samples containing different concentrations of 8-oxodG were sent to ESCULA members. Data were returned from 17 laboratories, representing 20 detection methods. There was good within-technique agreement for most of the laboratories. ELISA, however, showed more within-technique variation and reported higher 8-oxodG values. Overall, the study reveals greater consensus than previously expected, although some concern remains over ELISA.
  • The manuscript compares chromatographic and immunoassay methods used for the detection of urinary 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG). Samples containing different concentrations of 8-oxodG were sent to ESCULA members. Data were returned from 17 laboratories, representing 20 detection methods. There was good within-technique agreement for most of the laboratories. ELISA, however, showed more within-technique variation and reported higher 8-oxodG values. Overall, the study reveals greater consensus than previously expected, although some concern remains over ELISA. (en)
Title
  • Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.
  • Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress. (en)
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  • Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.
  • Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress. (en)
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  • RIV/68378041:_____/10:00350189!RIV11-AV0-68378041
http://linked.open...avai/riv/aktivita
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  • Z(AV0Z50390512)
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  • 4
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  • 293107
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  • RIV/68378041:_____/10:00350189
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  • DNA damage; DNA repair; immunoassay (en)
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  • US - Spojené státy americké
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  • [324F70D2EC2A]
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  • 24
http://linked.open...iv/tvurceVysledku
  • Rössner ml., Pavel
  • Šrám, Radim
  • Evans, M. D.
  • Olinski, R.
  • Loft, M. S.
http://linked.open...ain/vavai/riv/wos
  • 000276462300031
http://linked.open...n/vavai/riv/zamer
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  • 0892-6638
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