About: Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Using patch-clamp technique and immunohistochemical analysis, we investigated the changes in the expression of K+ channels in the rat hippocampal astrocytes and NG2-glia following global cerebral ischemia. We showed that the membrane properties of astrocytes after ischemia undergo complex alterations profoundly influencing the maintenance of K+ homeostasis in the damaged tissue, while NG2 glia display membrane currents typical of proliferating cells. Using patch-clamp technique and immunohistochemical analysis, we investigated the changes in the expression of K+ channels in the rat hippocampal astrocytes and NG2-glia following global cerebral ischemia. We showed that the membrane properties of astrocytes after ischemia undergo complex alterations profoundly influencing the maintenance of K+ homeostasis in the damaged tissue, while NG2 glia display membrane currents typical of proliferating cells. (en)
Title	Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus (en)
skos:prefLabel	Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus (en)
skos:notation	RIV/68378041:_____/10:00349049!RIV11-MSM-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(GA305/09/0717), P(GAP303/10/1338), P(LC554), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Butenko, Olena Pivoňková, Helena Anděrová, Miroslava Chvátal, Alexandr Benešová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	262960
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/10:00349049
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CNS injury; Patch-clamp; K+ channels (en)
http://linked.open.../riv/klicoveSlovo	CNS injury K+ channels Patch-clamp
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[F5392581F2B9]
http://linked.open...i/riv/nazevZdroje	Neurochemistry International
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Cell Therapy and Tissue Repair Neuroscience Centre Cell volume regulation in glial cells during brain ischemia/reperfusion Induction of neuro- and gliogenesis in rat brain after ischemia - the role of morphogenes and growth factors in the nervous tissue regeneration.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Benešová, Jana Pivoňková, Helena Anděrová, Miroslava Chvátal, Alexandr Butenko, Olena
http://linked.open...ain/vavai/riv/wos	000284437500011
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0197-0186
number of pages	12 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus

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