About: Noise exposure during early development impairs the processing of sound intensity in adult rats

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The study demonstrates that exposure to intense noise at postnatal day 14 produced not only poorer frequency selectivity of neurons in the inferior colliculus (as reported previously by Grecova et al. (2009) Eur. J. Neurosci. 29, 1921–1930), but affected significantly the neuronal representation of sound intensity. Although the response thresholds were similar in the exposed and control rats, the neurons in the exposed animals had a longer first-spike latency, a narrower dynamic range, lower maximum response magnitudes and a steeper slope of the rate–intensity functions. The observed anomalies were confined to the mid- and high-frequency regions, whereas no significant changes were found in the low-frequency neurons. The study demonstrates that exposure to intense noise at postnatal day 14 produced not only poorer frequency selectivity of neurons in the inferior colliculus (as reported previously by Grecova et al. (2009) Eur. J. Neurosci. 29, 1921–1930), but affected significantly the neuronal representation of sound intensity. Although the response thresholds were similar in the exposed and control rats, the neurons in the exposed animals had a longer first-spike latency, a narrower dynamic range, lower maximum response magnitudes and a steeper slope of the rate–intensity functions. The observed anomalies were confined to the mid- and high-frequency regions, whereas no significant changes were found in the low-frequency neurons. (en)
Title	Noise exposure during early development impairs the processing of sound intensity in adult rats Noise exposure during early development impairs the processing of sound intensity in adult rats (en)
skos:prefLabel	Noise exposure during early development impairs the processing of sound intensity in adult rats Noise exposure during early development impairs the processing of sound intensity in adult rats (en)
skos:notation	RIV/68378041:_____/10:00345712!RIV11-MSM-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/07/1336), P(LC554), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Popelář, Jiří Bureš, Zbyněk Syka, Josef Grécová, Jolana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	274954
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/10:00345712
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	auditory system; critical period; inferior colliculus (en)
http://linked.open.../riv/klicoveSlovo	critical period inferior colliculus auditory system
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2C71CF834BC0]
http://linked.open...i/riv/nazevZdroje	European Journal of Neuroscience
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Neuroscience Centre Acoustical signal processing in the neuronal circuits of the auditory system
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	32
http://linked.open...iv/tvurceVysledku	Bureš, Zbyněk Popelář, Jiří Syka, Josef Grécová, Jolana
http://linked.open...ain/vavai/riv/wos	000279612400017
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0953-816X
number of pages	10 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Noise exposure during early development impairs the processing of sound intensity in adult rats Noise exposure during early development impairs the processing of sound intensity in adult rats Noise exposure during early development impairs the processing of sound intensity in adult rats

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