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  • Aging, as well as many neurodegenerative diseases, is accompanied by serious cognitive deficits, particularly impaired learning and memory loss. Cognitive decline in old age has been linked to changes in brain anatomy, morphology, volume, and functional deficits. Nervous tissue, particularly in the hippocampus and cortex, is subject to various degenerative processes, including a decrease in the number and efficacy of synapses, neuronal loss, astrogliosis, and changes in extracellular matrix proteins. These and other changes not only affect the efficacy of signal transmission at synapses, but could also affect extrasynaptic (“volume) transmission, mediated by the diffusion of transmitters
  • Aging, as well as many neurodegenerative diseases, is accompanied by serious cognitive deficits, particularly impaired learning and memory loss. Cognitive decline in old age has been linked to changes in brain anatomy, morphology, volume, and functional deficits. Nervous tissue, particularly in the hippocampus and cortex, is subject to various degenerative processes, including a decrease in the number and efficacy of synapses, neuronal loss, astrogliosis, and changes in extracellular matrix proteins. These and other changes not only affect the efficacy of signal transmission at synapses, but could also affect extrasynaptic (“volume) transmission, mediated by the diffusion of transmitters (en)
Title
  • Aging: Extracellular Space
  • Aging: Extracellular Space (en)
skos:prefLabel
  • Aging: Extracellular Space
  • Aging: Extracellular Space (en)
skos:notation
  • RIV/68378041:_____/09:00340083!RIV10-AV0-68378041
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50390703)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 302160
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  • RIV/68378041:_____/09:00340083
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  • Alzheimer's; Dementia; Parkinson's (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [F08BAD813B09]
http://linked.open...i/riv/mistoVydani
  • New York
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  • Handbook of the Neuroscience of Aging
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Syková, Eva
http://linked.open...n/vavai/riv/zamer
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  • Academic Press
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  • 978-0-12-374898-0
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