About: Age-related changes in GAD levels in the central auditory system of the rat

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aging is associated with a decrease in the numbers of GAD65- and 67-immunoreactive neurons and the optical density of their somas in both the IC and AC, in addition, western blot analysis revealed a pronounced age-related decline in the levels of GAD65 and 67 proteins in both the IC and AC. For comparison, in the visual cortex the decrease in both proteins was less pronounced than in the IC and AC. Aging is associated with a decrease in the numbers of GAD65- and 67-immunoreactive neurons and the optical density of their somas in both the IC and AC, in addition, western blot analysis revealed a pronounced age-related decline in the levels of GAD65 and 67 proteins in both the IC and AC. For comparison, in the visual cortex the decrease in both proteins was less pronounced than in the IC and AC. (en) Stárnutí doprovází pokles počtu GAD65 a 67 pozitivních neuronů a pokles optické denzity pozitivních buněčných těl v colliculus inferior a sluchové kůře. Analýza pomocí western blotu ukázala i celkový pokles hladin obou proteinů v tkáni colliculus inferior a sluchové kůry. Pro srovnání, poklesy ve zrakové kůře byly také přítomné, ale menší než ve sluchové dráze. (cs)
Title	Age-related changes in GAD levels in the central auditory system of the rat Age-related changes in GAD levels in the central auditory system of the rat (en) Změny v obsahu GAD v centrálním sluchovém systému v závislosti na věku potkana (cs)
skos:prefLabel	Age-related changes in GAD levels in the central auditory system of the rat Age-related changes in GAD levels in the central auditory system of the rat (en) Změny v obsahu GAD v centrálním sluchovém systému v závislosti na věku potkana (cs)
skos:notation	RIV/68378041:_____/09:00316696!RIV09-MZ0-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/07/1336), P(LC554), P(NR8113), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Syka, Josef Burianová, Jana Ouda, Ladislav Profant, Olivier
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	302151
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/09:00316696
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Inferior colliculus; Auditory cortex; Rat (en)
http://linked.open.../riv/klicoveSlovo	Rat Auditory cortex Inferior colliculus
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[6B878F0DD042]
http://linked.open...i/riv/nazevZdroje	Experimental Gerontology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Neuroscience Centre Plasticity of hearing and sensorineural hearing impairment - from early development to presbycusis Acoustical signal processing in the neuronal circuits of the auditory system
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Syka, Josef Profant, Olivier Burianová, Jana Ouda, Ladislav
http://linked.open...ain/vavai/riv/wos	000264045300003
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0531-5565
number of pages	8 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Age-related changes in GAD levels in the central auditory system of the rat Age-related changes in GAD levels in the central auditory system of the rat Age-related changes in GAD levels in the central auditory system of the rat Age-related changes in GAD levels in the central auditory system of the rat

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