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  • 29 patients with advanced inoperable squamous head and neck cancer treated with radiotherapy with or without simultaneous chemotherapy were evaluated for their plasma TGF-beta1 levels prior to the treatment, in the middle of the radiotherapy course and at the end of the treatment. Neither pre-treatment nor post-treatment plasma TGF-beta1 level has a predictive value to the treatment response. The post-treatment plasma TGF-beta 1 level can predict late morbidity grade >1 in advanced head and neck cancor treated with radio(chemo)therapy. This could make a basis for dose escalation in selected patients.
  • 29 patients with advanced inoperable squamous head and neck cancer treated with radiotherapy with or without simultaneous chemotherapy were evaluated for their plasma TGF-beta1 levels prior to the treatment, in the middle of the radiotherapy course and at the end of the treatment. Neither pre-treatment nor post-treatment plasma TGF-beta1 level has a predictive value to the treatment response. The post-treatment plasma TGF-beta 1 level can predict late morbidity grade >1 in advanced head and neck cancor treated with radio(chemo)therapy. This could make a basis for dose escalation in selected patients. (en)
  • Studována byla prediktivní schopnost plasmatické hladiny TGF-beta1 u pacientů s pokročilými inoperabilními nádory hlavy a krku během radioterapie s anebo bez chemoterapie. Hodnoty neměly prediktivní význam pro odpověď na léčbu, ale hodnota plasmatického TGF-beta 1 po léčbě může predikovat pozdní morbiditu. (cs)
Title
  • Posttreatment plasma transforming growth factor beta 1 (TGF-beta1) level
  • Plasmatická hladina transformujícího růstového faktoru beta 1 (TGF-beta 1) predikuje pozdní morbiditu u pacientů s pokročilými tumory hlavy a krku (cs)
  • Posttreatment plasma transforming growth factor beta 1 (TGF-beta1) level (en)
skos:prefLabel
  • Posttreatment plasma transforming growth factor beta 1 (TGF-beta1) level
  • Plasmatická hladina transformujícího růstového faktoru beta 1 (TGF-beta 1) predikuje pozdní morbiditu u pacientů s pokročilými tumory hlavy a krku (cs)
  • Posttreatment plasma transforming growth factor beta 1 (TGF-beta1) level (en)
skos:notation
  • RIV/68378041:_____/05:00025713!RIV06-AV0-68378041
http://linked.open.../vavai/riv/strany
  • 393;397
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA5039202), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 537178
http://linked.open...ai/riv/idVysledku
  • RIV/68378041:_____/05:00025713
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • head and neck cancer; late morbidity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SK - Slovenská republika
http://linked.open...ontrolniKodProRIV
  • [8DC845EEB662]
http://linked.open...i/riv/nazevZdroje
  • Neoplasma
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 52
http://linked.open...iv/tvurceVysledku
  • Hozák, Pavel
  • Závadová, E.
  • Feltl, D.
  • Pála, M.
http://linked.open...n/vavai/riv/zamer
issn
  • 0028-2685
number of pages
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