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Description
  • Caspases are key enzymes activated during the 14 apoptotic machinery. Apoptosis as a way of programmed cell 15 death becomes deregulated in some pathologies including 16 cancer transformations, neurodegenerative, or autoimmune 17 diseases. Most of the methods available for the detection of 18 apoptosis and caspases provide qualitative information only or 19 quantification data as an average from cell populations or cell 20 lysates. Several reports point to the importance of more accu- 21 rate single-cell analyses in biomedical studies due to hetero- 22 geneity at tissue as well as cell level.
  • Caspases are key enzymes activated during the 14 apoptotic machinery. Apoptosis as a way of programmed cell 15 death becomes deregulated in some pathologies including 16 cancer transformations, neurodegenerative, or autoimmune 17 diseases. Most of the methods available for the detection of 18 apoptosis and caspases provide qualitative information only or 19 quantification data as an average from cell populations or cell 20 lysates. Several reports point to the importance of more accu- 21 rate single-cell analyses in biomedical studies due to hetero- 22 geneity at tissue as well as cell level. (en)
Title
  • A miniaturized device for bioluminescence analysis of caspase-3/7 5 activity in a single apoptotic cell
  • A miniaturized device for bioluminescence analysis of caspase-3/7 5 activity in a single apoptotic cell (en)
skos:prefLabel
  • A miniaturized device for bioluminescence analysis of caspase-3/7 5 activity in a single apoptotic cell
  • A miniaturized device for bioluminescence analysis of caspase-3/7 5 activity in a single apoptotic cell (en)
skos:notation
  • RIV/68081715:_____/14:00428917!RIV15-GA0-68081715
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GA14-28254S)
http://linked.open...iv/cisloPeriodika
  • 22
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 830
http://linked.open...ai/riv/idVysledku
  • RIV/68081715:_____/14:00428917
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • apoptosis; bioluminescence; single-cell analysis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [8C043D957244]
http://linked.open...i/riv/nazevZdroje
  • Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 406
http://linked.open...iv/tvurceVysledku
  • Klepárník, Karel
  • Lišková, Marcela
  • Adamová, Eva
  • Matalová, E.
http://linked.open...ain/vavai/riv/wos
  • 000340877200017
issn
  • 1618-2642
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00216-014-7949-7
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