About: Recent advances in the development of single cell analysis-A review

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Development of techniques for the analysis of the content of individual cells represents an important direction in modern bioanalytical chemistry. While the analysis of chromosomes, organelles, or location of selected proteins has been traditionally the domain of microscopic techniques, the advances in miniaturized analytical systems bring new possibilities for separations and detections of molecules inside the individual cells including smaller molecules such as hormones or metabolites. It should be stressed that the field of single cell analysis is very broad, covering advanced optical, electrochemical and mass spectrometry instrumentation, sensor technology and separation techniques. The number of papers published on single cell analysis has reached several hundred in recent years. Thus a complete literature coverage is beyond the limits of a journal article. The following text provides a critical overview of some of the latest developments with the main focus on mass spectrometry, microseparation methods, electrophoresis in capillaries and microfluidic devices and respective detection techniques for performing single cell analyses. Development of techniques for the analysis of the content of individual cells represents an important direction in modern bioanalytical chemistry. While the analysis of chromosomes, organelles, or location of selected proteins has been traditionally the domain of microscopic techniques, the advances in miniaturized analytical systems bring new possibilities for separations and detections of molecules inside the individual cells including smaller molecules such as hormones or metabolites. It should be stressed that the field of single cell analysis is very broad, covering advanced optical, electrochemical and mass spectrometry instrumentation, sensor technology and separation techniques. The number of papers published on single cell analysis has reached several hundred in recent years. Thus a complete literature coverage is beyond the limits of a journal article. The following text provides a critical overview of some of the latest developments with the main focus on mass spectrometry, microseparation methods, electrophoresis in capillaries and microfluidic devices and respective detection techniques for performing single cell analyses. (en)
Title	Recent advances in the development of single cell analysis-A review Recent advances in the development of single cell analysis-A review (en)
skos:prefLabel	Recent advances in the development of single cell analysis-A review Recent advances in the development of single cell analysis-A review (en)
skos:notation	RIV/68081715:_____/13:00398829!RIV14-MSM-68081715
http://linked.open...avai/predkladatel	Ústav analytické chemie AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(EE2.3.20.0182), P(GAP206/11/2377)
http://linked.open...iv/cisloPeriodika	OCT
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Foret, František Klepárník, Karel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav analytické chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	101683
http://linked.open...ai/riv/idVysledku	RIV/68081715:_____/13:00398829
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	single cell analysis; capillary electrophoresis; electrochemistry; microfluidic devices (en)
http://linked.open.../riv/klicoveSlovo	capillary electrophoresis microfluidic devices single cell analysis electrochemistry
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[0FA20B57973B]
http://linked.open...i/riv/nazevZdroje	Analytica Chimica Acta
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Single-cell analysis by mass spectrometry Development of Multidisciplinary Research and Educational Centrum for Bioanalytical Technologies
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	800
http://linked.open...iv/tvurceVysledku	Foret, František Klepárník, Karel
http://linked.open...ain/vavai/riv/wos	000325646100002
issn	0003-2670
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.aca.2013.09.004

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