About: Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA.

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Wild type of tumor suppressor p53 binds preferentially to supercoiled DNA in vitro both in the presence and absence of the p53 consensus sequence. This binding is decreased by physiological concentrations of unchelated zinc and partially by oxidation of the protein by diamide. Irreversibility of p53 oxidation was due to the removal of intrinsic zinc from its position in the DNA binding domain. Wild type of tumor suppressor p53 binds preferentially to supercoiled DNA in vitro both in the presence and absence of the p53 consensus sequence. This binding is decreased by physiological concentrations of unchelated zinc and partially by oxidation of the protein by diamide. Irreversibility of p53 oxidation was due to the removal of intrinsic zinc from its position in the DNA binding domain. (en)
Title	Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA. Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA. (en)
skos:prefLabel	Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA. Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA. (en)
skos:notation	RIV/68081707:_____/00:17010206!RIV/2003/AV0/A17003/N
http://linked.open.../vavai/riv/strany	177;183
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/99/0692), P(GA312/99/1550), P(NC5343), Z(AV0Z5004920), Z(MZ00020980501)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Paleček, Emil Černocká, Hana Pečinka, Petr Fojta, Miroslav Jagelská, Eva Brázda, Václav Paleček, Jan Brázdová, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	709843
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/00:17010206
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N/A (en)
http://linked.open.../riv/klicoveSlovo	N/A
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[5FA026682F37]
http://linked.open...i/riv/nazevZdroje	Journal of Biomolecular Structure and Dynamics. Conversation
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Structural aspects of interactions of checkpoint proteins with DNA The role of p53, p73 and IRF-1 proteins in regulation of the cell response do DNA damage Interaction of tumor supressor protein p53 with damaged DNA and with DNA lesions induced by anti-cancer drugs
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Brázda, Václav Brázdová, Marie Jagelská, Eva Paleček, Emil Černocká, Hana Paleček, Jan Pospíšilová, Š. Jovin, T. M. Vojtěšek, B. Pečinka, Petr Subramaniam, V. Fojta, Miloslav
http://linked.open...n/vavai/riv/zamer	Biophysical properties of living systems and their changes under the influence of environmental factors Biologické, genetické a epidemiologické aspekty malignit a optimalizace diagnosticko-léčebných postupů
issn	0739-1102
number of pages	7 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software