About: DNA Interactions of Antitumor Cisplatin Analogs Containing Enantiometric Amine Ligands.     Goto   Sponge   NotDistinct   Permalink

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Description
  • Modifications of natural DNA in cell-free media by the antitumor cisplatin analogs containing enantiomeric amine ligands were studied by various methods. It was found that both two isomers have similar binding site as cisplatin. Main differences resulting from modification of DNA by the enantiomers are the thermodynamical destabilization and conformational distortions of DNA.
  • Modifications of natural DNA in cell-free media by the antitumor cisplatin analogs containing enantiomeric amine ligands were studied by various methods. It was found that both two isomers have similar binding site as cisplatin. Main differences resulting from modification of DNA by the enantiomers are the thermodynamical destabilization and conformational distortions of DNA. (en)
Title
  • DNA Interactions of Antitumor Cisplatin Analogs Containing Enantiometric Amine Ligands.
  • DNA Interactions of Antitumor Cisplatin Analogs Containing Enantiometric Amine Ligands. (en)
skos:prefLabel
  • DNA Interactions of Antitumor Cisplatin Analogs Containing Enantiometric Amine Ligands.
  • DNA Interactions of Antitumor Cisplatin Analogs Containing Enantiometric Amine Ligands. (en)
skos:notation
  • RIV/68081707:_____/00:17000012!RIV/2003/AV0/A17003/N
http://linked.open.../vavai/riv/strany
  • 2008;2021
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/99/0695), P(IAA5004702), P(KSK2004601), P(OC D8.10), P(OC D8.50), Z(AV0Z5004920)
http://linked.open...iv/cisloPeriodika
  • N/A
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 709008
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/00:17000012
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • N/A (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [02CF994A61FC]
http://linked.open...i/riv/nazevZdroje
  • Biophysical Journal
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 78
http://linked.open...iv/tvurceVysledku
  • Brabec, Viktor
  • Malina, Jaroslav
  • Hofr, Ctirad
  • Natile, G.
  • Maresca, L.
http://linked.open...n/vavai/riv/zamer
issn
  • 0006-3495
number of pages
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