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  • We have found light dependent toxicity of different groups of Pcs on HaCaT cells. The most pronounced toxicity was elicited by Pcs with high positive densities at peripheral parts of substituent groups under illumination by white light. EC50 values for HaCaT cells are an order or two orders of magnitude higher than concentrations considered for management purposes in aquaculture, which indicate the safety of such applications for human or animal skin cells after the exposition. Nevertheless, more research including risk assessment should be done to confirm such conclusions.
  • We have found light dependent toxicity of different groups of Pcs on HaCaT cells. The most pronounced toxicity was elicited by Pcs with high positive densities at peripheral parts of substituent groups under illumination by white light. EC50 values for HaCaT cells are an order or two orders of magnitude higher than concentrations considered for management purposes in aquaculture, which indicate the safety of such applications for human or animal skin cells after the exposition. Nevertheless, more research including risk assessment should be done to confirm such conclusions. (en)
Title
  • Photodynamic effects of 31 different phthalocyanines on a human keratinocyte cell line
  • Photodynamic effects of 31 different phthalocyanines on a human keratinocyte cell line (en)
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  • Photodynamic effects of 31 different phthalocyanines on a human keratinocyte cell line
  • Photodynamic effects of 31 different phthalocyanines on a human keratinocyte cell line (en)
skos:notation
  • RIV/67985939:_____/13:00398140!RIV14-TA0-67985939
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  • I, P(TA01010356)
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  • 6
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  • 96090
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  • RIV/67985939:_____/13:00398140
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  • phthalocyanines; photodynamics; toxicity (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [E02EFB7999F7]
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  • Chemosphere
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  • 93
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  • Jančula, Daniel
  • Maršálek, Blahoslav
  • Babica, Pavel
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  • 000326857900004
issn
  • 0045-6535
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.chemosphere.2013.05.032
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