About: Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex

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About: Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	An algal extracellular biopolymer (over 8.5 105 Da) composed of carbohydrates (52%) and protein (13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose and its 3-O- and 4-O-methyl derivatives (63%), galactose (12%), glucuronic acid (11–12%), glucose (5%), rhamnose (4%), fucose (3–4%) and low content of others accompaning sugars. When tested on the citric acid-induced cough and reactivity of airways smooth muscle in vivo in the test system guinea pigs, this biopolymer assigned a significant cough suppressing effect. The reactivity of airways smooth muscle was not affected indicating that expectoration effect was not suppressed by biopolymer application, which is important from the pharmacological point of view. An algal extracellular biopolymer (over 8.5 105 Da) composed of carbohydrates (52%) and protein (13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose and its 3-O- and 4-O-methyl derivatives (63%), galactose (12%), glucuronic acid (11–12%), glucose (5%), rhamnose (4%), fucose (3–4%) and low content of others accompaning sugars. When tested on the citric acid-induced cough and reactivity of airways smooth muscle in vivo in the test system guinea pigs, this biopolymer assigned a significant cough suppressing effect. The reactivity of airways smooth muscle was not affected indicating that expectoration effect was not suppressed by biopolymer application, which is important from the pharmacological point of view. (en)
Title	Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex (en)
skos:prefLabel	Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex (en)
skos:notation	RIV/67985939:_____/11:00369361!RIV12-AV0-67985939
http://linked.open...avai/predkladatel	Botanický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0571), Z(AV0Z60050516)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Lukavský, Jaromír Cepák, Vladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Botanický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	204688
http://linked.open...ai/riv/idVysledku	RIV/67985939:_____/11:00369361
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Rhodella griesea; proteoglykan; cough (en)
http://linked.open.../riv/klicoveSlovo	Rhodella griesea cough proteoglykan
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[24907AE7D68A]
http://linked.open...i/riv/nazevZdroje	International Journal of Biological Macromolecules
http://linked.open...in/vavai/riv/obor	EF
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Bioindication and revitalization of toxic and antropogenic substrates and water sources: application of cyano bacteria, algae, soil bacteria and symbiotic fungi
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	49
http://linked.open...iv/tvurceVysledku	Lukavský, Jaromír Capek, P. Hindák, F. Ray, B. Breierová, E. Cepák, Vladislav Flešková, D. Jureček, Ľ. Nosál´ová, G. Turjan, J.
http://linked.open...ain/vavai/riv/wos	000296937200028
http://linked.open...n/vavai/riv/zamer	Struktura, funkce a evoluce biodiversity fotoautotrofních organismů a hub: původ a příčiny jejich proměnlivosti, dynamika populací, společenstev a ekosystémů; využití vybraných výsledků k rozvoji Průhonického parku
issn	0141-8130
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ijbiomac.2011.08.029
is http://linked.open...avai/riv/vysledek of	Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex

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