About: Transgenic miniature pig as a model for the study of Huntington´s Disease

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Transgenic miniature pig as a model for the study of Huntington´s Disease Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	As aged population grows, the number of people with age-related neurodegenerative disease is rising fast. Unfortunately, no known therapy is available to treat these diseases. The list of compounds could be used in treatment of neurodegenerative disorders but suitable animal model for pre-clinical tests is necessary to be generated. Miniature pig seems to be suitabla large animal model for simulating of neurodegenerative diseases. We have genetrated transgenic miniature pig as a model of Huntington´s disease which is caused by the mutation in huntingtin gene. Our current effort is focused on caharcterization of both pre-manifest and manifet stages of HD. As aged population grows, the number of people with age-related neurodegenerative disease is rising fast. Unfortunately, no known therapy is available to treat these diseases. The list of compounds could be used in treatment of neurodegenerative disorders but suitable animal model for pre-clinical tests is necessary to be generated. Miniature pig seems to be suitabla large animal model for simulating of neurodegenerative diseases. We have genetrated transgenic miniature pig as a model of Huntington´s disease which is caused by the mutation in huntingtin gene. Our current effort is focused on caharcterization of both pre-manifest and manifet stages of HD. (en)
Title	Transgenic miniature pig as a model for the study of Huntington´s Disease Transgenic miniature pig as a model for the study of Huntington´s Disease (en)
skos:prefLabel	Transgenic miniature pig as a model for the study of Huntington´s Disease Transgenic miniature pig as a model for the study of Huntington´s Disease (en)
skos:notation	RIV/67985904:_____/12:00424216!RIV14-AV0-67985904
http://linked.open...avai/predkladatel	Ústav živočišné fyziologie a genetiky AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Baxa, Monika
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	174908
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/12:00424216
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	transgenic pig; Huntington´s disease; large animal model; neurodegenerative disease (en)
http://linked.open.../riv/klicoveSlovo	Huntington´s disease large animal model transgenic pig neurodegenerative disease
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D3FBB55CCEFD]
http://linked.open...i/riv/nazevZdroje	Bioprospect
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Baxa, Monika
issn	1210-1737
number of pages	3 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 117 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software