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  • Essential oils are plant secondary metabolites with positive pharmacological properties, e.g. anti-oxidative, antimicrobial or immunomodulative, but they can have toxic and allergic effects as well. The aim of this study was to analyze anti-inflammatory effects of chamomile essential oil dietary administration in carrageenan paw oedema and trinitrobenzene sulfonic acid (TNBS) colitis. Mice received chamomile essential oil in three concentrations (5000, 2500 and 1250 ppm) in the standard rodent diet starting two weeks before induction of carrageenan paw oedema and TNBS colitis. Dietary supplementations with 5000 ppm of chamomile essential oil significantly reduced both the oedema and the weight of mice paws compared with control. The same dose of chamomile essential oil showed protective effect on colonic mucosa and improved macroscopic signs of TNBS-induced colonic inflammation.
  • Essential oils are plant secondary metabolites with positive pharmacological properties, e.g. anti-oxidative, antimicrobial or immunomodulative, but they can have toxic and allergic effects as well. The aim of this study was to analyze anti-inflammatory effects of chamomile essential oil dietary administration in carrageenan paw oedema and trinitrobenzene sulfonic acid (TNBS) colitis. Mice received chamomile essential oil in three concentrations (5000, 2500 and 1250 ppm) in the standard rodent diet starting two weeks before induction of carrageenan paw oedema and TNBS colitis. Dietary supplementations with 5000 ppm of chamomile essential oil significantly reduced both the oedema and the weight of mice paws compared with control. The same dose of chamomile essential oil showed protective effect on colonic mucosa and improved macroscopic signs of TNBS-induced colonic inflammation. (en)
Title
  • ANTI-INFLAMMATORY EFFECTS OF CHAMOMILE ESSENTIAL OIL IN MICE
  • ANTI-INFLAMMATORY EFFECTS OF CHAMOMILE ESSENTIAL OIL IN MICE (en)
skos:prefLabel
  • ANTI-INFLAMMATORY EFFECTS OF CHAMOMILE ESSENTIAL OIL IN MICE
  • ANTI-INFLAMMATORY EFFECTS OF CHAMOMILE ESSENTIAL OIL IN MICE (en)
skos:notation
  • RIV/67985904:_____/11:00367752!RIV12-AV0-67985904
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 186452
http://linked.open...ai/riv/idVysledku
  • RIV/67985904:_____/11:00367752
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • inflammation; carrageenan paw oedema; TNBS colitis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SK - Slovenská republika
http://linked.open...ontrolniKodProRIV
  • [6233A3EDAA37]
http://linked.open...i/riv/nazevZdroje
  • Slovak Journal of Animal Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 44
http://linked.open...iv/tvurceVysledku
  • Bujňáková, D.
  • Bukovska, A.
  • Fabian, D.
  • Grešáková, L.
  • Juhás, Štefan
  • Koppel, J.
http://linked.open...n/vavai/riv/zamer
issn
  • 1335-3683
number of pages
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