About: Molecular basis of tooth germ development

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Detailní znalosti o normálním vývoji zubů jsou nezbytným předpokladem pro porozumění zubním defektům na molekulární úrovni a pro jejich možnou terapii založenou na tkáňovém inženýrství. Tento článek má za cíl shrnout zýkladní kroky odontogenetických kaskád.Především bude diskutována role Shh (sonic hedgehog), Wnts/wingless-type MMTV integration site family), Fgf (fibroblast growth factor) a Bmp (bone morphogenetic proteins) proteinových rodin v jednotlivých fázích vývoje od iniciace po tvorbu tvrdých tkání zubu. (cs) Detailed information about normal tooth development is an essential prerequisite for understanding dental defects at molecular level and their possible tissue engineering based therapy. This review aims to briefly summarise keystones of odontogenetic molecular networks. Particularly, involvement of Shh (sonic hedgehog), Wnts/wingless-type MMTV integration site family), Fgf (fibroblast growth factor) and Bmp (bone morphogenetic proteins)families in different stages of normal tooth development from initiation to hard tissues formation is discussed. Detailed information about normal tooth development is an essential prerequisite for understanding dental defects at molecular level and their possible tissue engineering based therapy. This review aims to briefly summarise keystones of odontogenetic molecular networks. Particularly, involvement of Shh (sonic hedgehog), Wnts/wingless-type MMTV integration site family), Fgf (fibroblast growth factor) and Bmp (bone morphogenetic proteins)families in different stages of normal tooth development from initiation to hard tissues formation is discussed. (en)
Title	Molecular basis of tooth germ development Molecular basis of tooth germ development (en) Molekulární podstata vývoje zubních zárodků (cs)
skos:prefLabel	Molecular basis of tooth germ development Molecular basis of tooth germ development (en) Molekulární podstata vývoje zubních zárodků (cs)
skos:notation	RIV/67985904:_____/07:00090276!RIV08-AV0-67985904
http://linked.open.../vavai/riv/strany	39;46
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KJB500450503), P(OC B23.001), Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Míšek, Ivan Matalová, Eva Fleischmannová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	434838
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/07:00090276
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	tooth germ development (en)
http://linked.open.../riv/klicoveSlovo	tooth germ development
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[26605853A420]
http://linked.open...i/riv/nazevZdroje	Ortodoncie
http://linked.open...in/vavai/riv/obor	FF
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Modulations of intracellular caspase machinery in early odontogenesis http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20B23.001
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	16
http://linked.open...iv/tvurceVysledku	Míšek, Ivan Matalová, Eva Krejčí, P. Fleischmannová, Jana
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	1210-4272
number of pages	8 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Molecular basis of tooth germ development Molecular basis of tooth germ development Molecular basis of tooth germ development

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