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| Description
| - The influence of polymeric nanoparticles on the rheological and electrical properties of RBC suspensions has been studied. Poly(acrylic acid) particles of different architecture and molecular weight were used, that is, a new core–shell type star polymer whose interior presents hyperbranched polystyrene bearing arms of poly(acrylic acid) and linear polyacrylic chains with average molecular weights Mn=225 000, 20 000 and 6 000. The star macromolecules possessed in average ten arms with degree of polymerization DP=58. Their shape is spherical with hydrodynamic radius Rh=14 nm determined by the diffusion ordered NMR spectroscopy [1]. On the other hand, the linear poly(acrylic acid) chains adopt rod like form under physiological conditions. Suspensions of polymeric nanoparticles in physiological solution with different mass/number of particle concentration were prepared. The volumetric particle concentrations used in the experiments with red blood cell (RBC) suspensions were 1mg/ml (1.1x1016 particles/ml) and 0.2mg/ml (2.1x1016 particles/ml). RBC suspension conductivity under steady and unsteady flow conditions was measured by means of electro-rheological technique. The technique is based on the measurement of dielectric properties of dispersed systems in Couette viscometric flow. The main advantage of this procedure is that blood is subjected in the Couette rheometric cell to uniform shearing field and information about mechanical and electrical properties of the fluid is obtained in parallel. The apparent viscosity of RBC suspensions in the presence of nanoparticles, as well as, the control without particles were measured using a rotational viscometer Contraves Low Shear 30 at steady and unsteady flows at shear rates from 0.0237 s-1 to 128.5 s-1 and temperature 37 oC. The results show that RBC suspensions conductivity and the apparent viscosity are dependent on the investigated factors as the shape, concentration and molecular weight of nanoparticles.
- The influence of polymeric nanoparticles on the rheological and electrical properties of RBC suspensions has been studied. Poly(acrylic acid) particles of different architecture and molecular weight were used, that is, a new core–shell type star polymer whose interior presents hyperbranched polystyrene bearing arms of poly(acrylic acid) and linear polyacrylic chains with average molecular weights Mn=225 000, 20 000 and 6 000. The star macromolecules possessed in average ten arms with degree of polymerization DP=58. Their shape is spherical with hydrodynamic radius Rh=14 nm determined by the diffusion ordered NMR spectroscopy [1]. On the other hand, the linear poly(acrylic acid) chains adopt rod like form under physiological conditions. Suspensions of polymeric nanoparticles in physiological solution with different mass/number of particle concentration were prepared. The volumetric particle concentrations used in the experiments with red blood cell (RBC) suspensions were 1mg/ml (1.1x1016 particles/ml) and 0.2mg/ml (2.1x1016 particles/ml). RBC suspension conductivity under steady and unsteady flow conditions was measured by means of electro-rheological technique. The technique is based on the measurement of dielectric properties of dispersed systems in Couette viscometric flow. The main advantage of this procedure is that blood is subjected in the Couette rheometric cell to uniform shearing field and information about mechanical and electrical properties of the fluid is obtained in parallel. The apparent viscosity of RBC suspensions in the presence of nanoparticles, as well as, the control without particles were measured using a rotational viscometer Contraves Low Shear 30 at steady and unsteady flows at shear rates from 0.0237 s-1 to 128.5 s-1 and temperature 37 oC. The results show that RBC suspensions conductivity and the apparent viscosity are dependent on the investigated factors as the shape, concentration and molecular weight of nanoparticles. (en)
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| Title
| - Influence of polymeric nanoparticles on rheological and electrical properties of RBC suspensions
- Influence of polymeric nanoparticles on rheological and electrical properties of RBC suspensions (en)
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| skos:prefLabel
| - Influence of polymeric nanoparticles on rheological and electrical properties of RBC suspensions
- Influence of polymeric nanoparticles on rheological and electrical properties of RBC suspensions (en)
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| skos:notation
| - RIV/67985874:_____/13:00398476!RIV14-AV0-67985874
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| http://linked.open...avai/predkladatel
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/67985874:_____/13:00398476
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - RBC suspensions; polymeric nanoparticles; rheological properties; electrical properties (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...v/mistoKonaniAkce
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...i/riv/nazevZdroje
| - Clinical Hemorheology and Microcirculation
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Říha, Pavel
- Antonova, N.
- Ivanov, I.
- Koseva, N.
- Kowalczyk, A.
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| http://linked.open...vavai/riv/typAkce
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| http://linked.open.../riv/zahajeniAkce
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| issn
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| number of pages
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| http://purl.org/ne...btex#hasPublisher
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